The aim of this study was to evaluate the radiographic outcomes obtained in a sample of patients treated with a chiropractic scoliosis-specific exercise program for patients with adolescent idiopathic scoliosis. Patients were treated and subsequently followed through skeletal maturity, and their results were reported in accordance with the SOSORT Consensus Guidelines. A total of 60 patient char...

We assessed whether there is a recognisable pattern of facial morphology in photographs of a series of 62 children with idiopathic congenital talipes equinovarus (CTEV). Photographs were scored for a number of facial characteristics by a research team comprising orthopaedic surgeons and clinical geneticists, to identify a subgroup of children with idiopathic CTEV, who shared characteristic faci...

A case of idiopathic scrotal oedema is presented in detail and the aetiology, diagnosis and treatment considered with references to the literature available.

The natural history and optimal treatment for idiopathic toe walking are unknown. The literature is full of poorly documented treatment regimens with few even medium term follow up studies. The senior author reports his nearly 30 year approach to this disorder and his failed attempt to perform a follow up study of his particular treatment regimen. We conclude with our considered interpretation ...

This was a prospective study on the association of brace compliance and curve progression in idiopathic scoliosis. Compliance was measured electronically by embedding a temperature sensor and logger in the Wilmington scoliosis brace. To date there have been no studies that relate objective measures of compliance in a scoliosis brace to treatment outcomes. Thirty-four subjects with idiopathic sc...

BACKGROUND The North American non-surgical standard of care for adolescent idiopathic scoliosis (AIS) includes observation and bracing, but not exercises. Schroth physiotherapeutic scoliosis-specific exercises (PSSE) showed promise in several studies of suboptimal methodology. The Scoliosis Research Society calls for rigorous studies supporting the role of exercises before including it as a tre...

Gorham's disease is a rare benign cause of progressive massive idiopathic osteolysis. The clinician's acute awareness and high degree of suspicion are required for diagnosis because of its rarity and variable clinical presentation. Distinctive radiological and histopathological features may help in this regard. Though eventual stabilisation of the affected bone is the most common sequel, sponta...

FDE characteristically occurs each time the offending drug is administrated, although the number of involved sites may increase. The pathogenesis of the disease is still obscure. It seems that a large homogenous population of CD8 (+) T cells are distributed along the epidermal basal layer in FDE and have the capacity to produce large amounts of IFNgamma. These cells are likely to play a signifi...

In this paper a theory is developed that provides the sampling distribution of alleles at a diallelic marker locus closely linked to a low-frequency allele that arose as a single mutant. The sampling distribution provides a basis for maximum-likelihood estimation of either the recombination rate, the mutation rate, or the age of the allele, provided that the two other parameters are known. This...