نتایج جستجو برای: hypercvad

تعداد نتایج: 72  

Journal: :Haematologica 2005
Ashley P Ng Leon Worth Luke Chen John F Seymour H Miles Prince Monica Slavin Karin Thursky

BACKGROUND AND OBJECTIVES Despite increasing intensity and profound immunosuppression associated with newer therapies for hematologic malignancies, little information exists regarding cytomegalovirus (CMV) reactivation in settings other than allogeneic stem cell transplantation (SCT). DESIGN AND METHODS We reviewed the epidemiology of CMV disease in patients who were CMV polymerase chain reac...

2004
Deborah A. Thomas Stefan Faderl Jorge Cortes Susan O’Brien Francis J. Giles Steven M. Kornblau Guillermo Garcia-Manero Michael J. Keating Michael Andreeff Sima Jeha Miloslav Beran Srdan Verstovsek Sherry Pierce Laurie Letvak August Salvado Richard Champlin Moshe Talpaz Hagop Kantarjian

Imatinib mesylate, an inhibitor of the BcrAbl tyrosine kinase, has modest activity in refractory/relapsed Philadelphia chromosome (Ph)–positive acute lymphocytic leukemia (ALL). Use of concurrent chemotherapy and imatinib mesylate in newly diagnosed Ph-positive ALL was explored. There were 20 patients who received hyper–CVAD (cyclophosphamide, vincristine, Adriamycin, and dexamethasone) and ima...

Journal: :Seminars in oncology 2006
Preetesh Jain Susan O'Brien

Richter's transformation, or Richter's syndrome, is an uncommon clinicopathological condition observed in about 5% to 10% of patients with chronic lymphocytic leukemia (CLL). "Richter's transformation" refers to the development of aggressive lymphoma during the course of CLL. Diffuse large B-cell lymphoma occurs in the majority of cases of Richter's transformation. Clinically, patients with Ric...

Journal: :Haematologica 2003
Giuseppe Todeschini

Dear Sirs, I read with interest the article by Zinzani et al 1 and Lazzarino's comment 2 about the treatment of mediastinal large B-cell lymphoma (MLBCL), in December issue of Haematologica. I believe too that CHOP is not the best treatment for MLBCL, since we observed significantly better results with third generation therapies . These preliminary results are confirmed by Zinzani's recent pape...

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