Four known tropane alkaloids were isolated from the leaves of the endemic Chilean plant Latua pubiflora (Solanaceae). For the first time; 3alpha-cinnamoyloxitropane and apoatropine are reported in this plant. Scopolamine and hyoscyamine were previously reported.

The purpose of the present study was to determine the tropane alkaloid content of four Hyoscyamus species from Iran, i.e. H. pusillus L., H. niger L., H. reticulatus L. and H. kurdicus Bornm. Determination of alkaloids was performed by the HPLC method. Samples were extracted with chloroform-methanol-25% ammonium hydroxide 15:5:1 (V/V/V). HPLC separation was performed on Eurospher C18 reversed p...

Ninety patients with duodenal ulcer, divided randomly into three groups, were treated continuously for one year with either glycopyrronium, 1-hyoscyamine (as a sustained-release preparation) or inert tablets. Dosage with active tablets was so adjusted that the patient experienced definite but tolerable side-effects. Basal and maximal gastric acid secretion were measured immediately before and o...

Thirty-six alkaloids were identified in the organs of Datura ceratocaula by GC/MS. Thirty-three of them have not been previously reported for the species. Furthermore, a new tropane ester was tentatively identified as 3-(3'-formyloxytropoyloxy)tropane on basis of its mass spectral fragmentation. Hyoscyamine was the main alkaloid in the plant organs.

Tropane alkaloids such as scopolamine (C17H21NO4), atropine (C17H23NO3) and hyoscyamine (C17H23NO3) are the most important plant secondary metabolites in the pharmaceutical industry due to anticholinergic activity, competition with muscarinic receptors and also treating different human diseases. Scopolamine, hyoscyamine and atropine are the most important tropane alkaloids used as anticoagulant...

Atropine is one of the commonly used drugs for clinical treatment livestock and poultry, as well animal emergency treatment. Its main components are d-hyoscyamine L-hyoscyamine. a toxic colorless, odorless or white crystalline alkaloid extracted from belladonna other solanaceous plants. It neutral weakly acidic when dissolved in water. mainly an m-receptor blocker, belonging to anticholinergic ...

This study was aimed to determine the effects of different concentrations L-phenylalanine (0.25, 0.50 and 1.00 mM L-Phe) applied adventitious root cultures for culture durations on growth production tropane alkaloids phenolics in Hyoscyamus niger. For this purpose, roots obtained from petiole explants vitro seedlings were used as plant materials. After cultured liquid Murashige Skoog (MS) mediu...