OBJECTIVES Midazolam with variable dosages has been used to induce sedation in pediatric dentistry. The aim of this study was to compare the efficacy of two dosages of oral midazolam for conscious sedation of children undergoing dental treatment. MATERIALS AND METHODS In this randomized crossover double blind clinical trial, 20 healthy children (ASA I) aged three to six years with definitely ...

a chemiluminescence (cl) method has been developed for the determination of hydroxyzine (hyd) and its metabolite cetirizine (cet). the method is based on sensitizing effect of cet and hyd on the weak cl reaction between ru(phen)32+ and acidic ce(iv). a mechanism for the cl reaction has been proposed on the basis of uv-vis, fluorescent and cl spectra. by using the recommended procedure, the cali...

background: to perform screening for colonic cancer and to diagnose other colic diseases, colonoscopies are required. comfort of patient during colonoscopy is very important. currently, there are two types of sedation used during colonoscopy-the general anesthesia and sedoanalgesia. sedo-analgesia is the most frequently used type of sedation employed during colonoscopy worldwide. materials and ...

in light of the high prevalence of sleep disorders in patients suffering from post-traumatic stress disorders (ptsd), this study sought to comparing the effect of prazosin and hydroxyzine on sleep quality in this patient group. a total 100 patients suffering from ptsd were assessed (mean age: m = 35.51, sd = 6.41 28% females). next, they were randomly assigned to one of three treatment groups: ...

In light of the high prevalence of sleep disorders in patients suffering from post-traumatic stress disorders (PTSD), this study sought to comparing the effect of prazosin and hydroxyzine on sleep quality in this patient group. A total 100 patients suffering from PTSD were assessed (mean age: M = 35.51, SD = 6.41 28% females). Next, they were randomly assigned to one of three treatment groups: ...

Antihistaminic drugs are commonly used as symptomatic therapy of atopic dermatitis in dogs. Unfortunately, their clinical benefit is largely unsubstantiated. In a double-blinded, placebo-controlled, cross-over trial, the influence of dimetinden and of a combination of chlorpheniramine and hydroxyzine on pruritus and lesions was evaluated in 19 dogs. They were treated with either product or a pl...

The purpose of this study was to compare the effectiveness of triazolam to chloral hydrate with hydroxyzine when sedating young children for dental treatment. Twenty children, age 21 to 74 months, with a mean age of 44 months, were given triazolam. Twenty children, age 23 to 64 months, with a mean age of 42 months, were given chloral hydrate with hydroxyzine. The children were given an elixir o...

Objectives The aim of this clinical trial was to compare the effects of oral Midazolam with oral Hydroxyzine on post sedation using IV Ketaminein children. Methods This single blind cross over clinical trial, was conducted on 25 children aged 2-6 years of ASA I and definitely negative by Frankl behavioral scale. Participants were divided into two groups: Group I received hydroxyzine syrup prem...