A series of hydroxypropylated starch (HPS) that can be dissolved in water at 60–65 °C was obtained via two-step method system from corn starch. The structure and property the HPS its gelatinization temperature were characterized by Fourier transform infrared spectrometer, nuclear magnetic resonance spectroscopy (1H NMR), X-ray diffraction (XRD), differential scanning calorimetry (DSC), electron...

The sustained release tablets were formulated by using the combination of various retardant polymers/excipient. polymers used hydroxypropyl methylcellulose, Micro Crystalline Cellulose and Sodium starch glycolate. present investigation involves formulation evaluation Valsartan with a view to prolong drug in gastrointestinal tract consequently into plasma. It showed good linearity reproducibilit...

The objective of this study was to investigate the swelling characteristics of various swellable polymers in swelling layers that induce the rupturing of an outer polymer coating in pulsatile drug delivery systems (DDS). An apparatus was designed to measure simultaneously the swelling energy/force and water uptake of discs, made of polymers. The swelling energy of several excipients decreased i...

Famotidine is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol. Each tablet for oral administration contains either 20 mg or 40 mg of famotidine and the following inactive ingredients: hydroxypropyl cellulose, hypromellose, iron oxides, magnesium stearate,...

The aqueous two-phase system (ATPS) with polyethylene glycol (PEG) and hydroxypropyl starch (HPS) was evaluated for the extraction of human immunoglobulin G (IgG) from human serum albumin (HSA). The partitions of IgG in PEG/sulphate, PEG/phosphate, PEG/Dextran and PEG/HPS ATPSs were compared, and the results indicated that PEG/HPS system was most suitable for IgG extraction. The effects of the ...

The study reports on the preparation of nanocrystalline cellulose from waste papers (WPNCC), as an environmental friendly approach source material and investigation their effects morphological, mechanical barrier properties Hydroxypropyl methylcellulose/Cationic starch (HPMC/CS) nanocomposites. HCl hydrolysis followed by alkali treatment deinking fibers resulted in production WPNCC. Also, HPMC/...

Different types of starches were used to prepare controlled release tablets loaded with diprophylline by direct compression. The impact the natural origin starch, potential chemical modifications (e.g., cross-linking phosphate or adipate, hydroxypropylation, acetylation different degrees, partial hydrolysis) and type pre-gelatinization process (laboratory scale ethanol oven drying versus indust...

The present study was undertaken to examine the effect of pH and concentration of hydroxypropyl-beta-cyclodextrin on the solubility of carvedilol as it shows pH-dependent solubility. The equilibrium solubility of carvedilol in a series of solutions of varying pH (from 1.2 to 11) was determined and compared with the equilibrium solubility of carvedilol in the presence of 20% hydroxypropyl-beta-c...