OBJECTIVE Allium elburzense is an endemic plant of the family Amaryllidaceae that grows wild in northern Iran with some nutritional and medicinal applications. The present study was aimed to investigate the fibrinolytic and antioxidant effects of A. elburzense bulb extracts. MATERIALS AND METHODS Hydroalcoholic, aqueous, chloroformic and butanolic extracts were evaluated in this research. In ...

This study was undertaken to investigate the possible effect of hydroalcoholic root extract of Rubia cordifolia against indomethacin-induced enterocolitis in rats. Male Wistar rats received vehicle or hydroalcoholic root extract of Rubia cordifolia (300 and 600 mg/kg) for 11 consecutive days. Enterocolitis was induced by subcutaneous administration of indomethacin (7.5 mg/kg) on 8(th) and 9(th)...

OBJECTIVE The present study aimed to evaluate the sedative and anxiolytic effects of the essential oils and hydroalcoholic extract of Kelussia odoratissima Mozaff. (K. odoratissima) in mice by utilizing an elevated plus maze. The chemical composition of its essential oil was also determined. METHODS The hydroalcoholic extract or essential oil fraction from this plant were administered intrape...

OBJECTIVE This study was designed to investigate the effect of hydroalcoholic extract and essential oil of Heracleum persicum (Apiaceae) on lipid profile of male hyperlipidemic rabbits. MATERIALS AND METHODS Thirty rabbits were randomly divided into six groups of five each. One group received normal diet and the other groups fed with a high cholesterol (2% W/W) diet for 7 weeks. Vehicle, hydr...

Recently a potent anti-inflammatory effect of hydroalcoholic extract of the aerial parts of the sterile stems of Stachys inflata has been reported. This study examined whether hydroalcoholic extract isolated from aerial parts of non-flowering stems of Stachys inflata (standardized to contain 4.5% caffeic acid derivatives) reduce myocardial infarct size arising from coronary artery occlusion (30...

introduction: despite extensive studies about effects of crataegus monogyna on cardiovascular diseases yet, a few study has been undertaken antiarrhythmic property of this plant. aims of the present study were: 1) to determine the protective role of methanolic extract of c.monogyna on the rate-dependent model and the concealed conduction . 2) to explore the role of na+-k+ a tpase in the protect...

the stimulatory effect of the extract of portulaca oleracea (p. olerace) on β-adrenoceptor of tracheal smooth muscle was examined. to examine β-adrenoceptor stimulatory effect, concentration response curve to isoprenaline was obtained in pre-contracted tracheal smooth muscle in the presence of three concentrations of aqueous-ethanolic extract, propranolol and saline. values of ec50 (the effecti...

OBJECTIVE At present, there are many antiepileptic drugs with a wide range of side effects on the human body. It was assumed that Zataria multiflora Boiss (Z. multiflora) with sedative, anti-spasmodic and anti-inflammatory activity may be effective in the treatment of epilepsy. The aim of the present study was to elucidate the effect of Z. multiflora hydroalcoholic extract and its fraction extr...

objective: achillea millefolium (a. millefolium) is known as an orexigenic herb in iranian traditional medicine. in this study, the possible orexigenic effect of hydro-alcoholic extract of a. millefolium was investigated by measuring plasma ghrelin level.materials and methods: thirty male wistar rats were divided into five groups. control group received water. treatment groups received 50, 100 ...

PURPOSE To investigate the effects of hydroalcoholic leaf extract of Mikania glomerata Spreng (Asteraceae) on the activity of Bothrops jararaca snake venom in Wistar rats. METHODS Fifty four rats Wistar were divided into six groups of nine animals in each: control treated with saline; control treated with B. jararaca venom; control treated with M. glomerata extract; B. jararaca venom incubate...