The development of low profile gamma-ray detectors has encouraged the production of small field of view (SFOV) hand-held imaging devices for use at the patient bedside and in operating theatres. Early development of these SFOV cameras was focussed on a single modality-gamma ray imaging. Recently, a hybrid system-gamma plus optical imaging-has been developed. This combination of optical and gamm...

Since the 1990s, hybrid imaging by means of software and hardware image fusion alike allows the intrinsic combination of functional and anatomical image information. This review summarises in three parts the state-of-the-art of dual-technique imaging, with a focus on clinical applications. We will attempt to highlight selected areas of potential improvement of combined imaging technologies and ...

Since its invention in the 1960s, computed tomography (CT) has become an indispensable technique of biomedical imaging. Numerous modalities have been introduced since then, including the traditional Xray CT scan, SPECT, MRI, Optical-, Ultrasound-, and Electrical Impedance Tomography, with many others being currently developed. All these techniques are used to obtain images of the internal struc...

E. Y. Wong, C. M. Hillenbrand, J. S. Lewin, J. L. Duerk Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, Department of Radiology, University Hospitals of Cleveland, Cleveland, OH, United States Introduction The use of MRI in minimally invasive, intravascular therapeutic procedures, has increased the need for imaging coils that provide accurate...

Diffusion measurements in the human central nervous system are complex to characterize and a broad spectrum of methods have been proposed. In this study, a comprehensive diffusion encoding and analysis approach, hybrid diffusion imaging (HYDI), is described. The HYDI encoding scheme is composed of multiple concentric "shells" of constant diffusion weighting, which may be used to characterize th...