Viruses have evolved different strategies to interfere with host cell apoptosis. Herpesvirus saimiri (HVS) and other lymphotropic herpesviruses code for proteins that are homologous to the cellular antiapoptotic Bcl-2. In this study HVS-Bcl-2 was stably expressed in the human leukemia cell line Jurkat and in the murine T-cell hybridoma DO to assess its antiapoptotic spectrum and to gain further...

In this paper some Human Visual System (HVS) models used in digital image watermarking are presented. Four different HVS models, which exploit various properties of human eye, are described. Two of them operate in transform domain of Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT). HVS model in DCT domain consists of Just Noticeable Difference thresholds for corresponding D...

OBJECTIVES To describe the management of vaginal discharge in general practice, with particular regard to the use of the high vaginal swab (HVS), and to compare GPs' expectations of this test with the processing and reporting undertaken by different laboratories. METHODS A postal questionnaire survey of 2146 GPs in the North Thames area and postal questionnaire study of the 22 laboratories se...

Hyperventilation syndrome (HVS) often occurs under stressful conditions, and has been reported during or after anesthesia and operation. HVS, characterized by multiple somatic symptoms and electrolyte imbalances induced by inappropriate hyperventilation, should be managed as an emergency. We report a rare case of HVS during spinal anesthesia. The patient was a previously healthy 51-year-old fem...

Herpesvirus saimiri (HVS) transforms human T cells to stable growth in vitro. Since HVS codes for two different antiapoptotic proteins, growth transformation by HVS might be expected to confer resistance to apoptosis. We found that the expression of both viral antiapoptotic genes was restricted to cultures with viral replication and absent in growth-transformed human T cells. A comparative exam...

Despite the absence of randomized trials, plasmapheresis has consistently demonstrated efficacy in treatment of Waldenström's macroglobulinemia (WM) patients with hyperviscosity syndrome (HVS). This procedure can promptly reverse most clinical manifestations of serum HVS. Early diagnosis is crucial and usually can be made from the funduscopic exam. Serial viscosity measurements can be monitored...

We give an overview of fields of study, related with modelling of the human visual system and perception of visual information – HVS anatomy and physiology, HVS modelling, and visual quality metrics. We present the state‐of‐the‐art in HVS modelling, including single and multichannel models, and models of specific HVS properties – light adaptation, contrast sensitivity, spatiotemporal masking. W...

BACKGROUND Leber hereditary optic neuropathy (LHON) is a maternally inherited form of retinal ganglion cell degeneration leading to optic atrophy in young adults. It is caused by three primary point mutations including G11778A, G3460A, and T14484C in the mitochondrial genome. These three mutations account for the majority of LHON cases and affect genes that encode for different subunits of mito...

BACKGROUND The Koreans are generally considered a northeast Asian group because of their geographical location. However, recent findings from Y chromosome studies showed that the Korean population contains lineages from both southern and northern parts of East Asia. To understand the genetic history and relationships of Korea more fully, additional data and analyses are necessary. METHODOLOGY...

We have performedN -body simulations of the formation of hyper-velocity stars (HVS) in the centre of the Milky Way due to inspiralling intermediate-mass black holes (IMBHs). We considered IMBHs of different masses, all starting from circular orbits at an initial distance of 0.1 pc. We find that the IMBHs sink to the centre of the Galaxy due to dynamical friction, where they deplete the central ...