Adeno-associated virus (AAV) is a member of the family Parvoviridae that has been widely used as a vector for gene therapy because of its safety profile, its ability to transduce both dividing and non-dividing cells, and its low immunogenicity. AAV has been detected in many different tissues of several animal species but has not been associated with any disease. As a result of natural infection...

this study examined the possible effects of lycopene at physiological dosage and body fat mass on the humoral immune response in patients with type 2 diabetes mellitus (t2dm). a total of 35 patients with typ2 diabetes mellitus from both sexes aged 54±9 yrs from the iranian diabetes society were introduced into a double blind placebo controlled clinical trial conducted for 2 months. after a 2-we...

Memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. The main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. Mice were immunized with human immunodeficiency virus-1 P24-Nef fusion peptide and then cellular and humoral immune responses were evaluated. In order to determin...

Although vaccination against Salmonella has been used more frequently in broiler breeders in recent years, there is limited information in the literature demonstrating the immunological response of combinations of live and killed whole cell vaccines. The present research assesses the immunological response generated by three different vaccination protocols. Treatment vaccines consisted of a liv...

Growth Response and Humoral Immunity of Broiler Chickens Fed Organic Acids Zeolite Coated with Silver Nanoparticles under Heat Stress Conditions

Propoxure (PPX) is a well-known carbamate insecticide, which has been used for several decades in the world and Iran in agriculture and public health programs. However, there is no clear investigation toward its immunotoxicity as yet. In this study, we examined the effects of subchronic i.p. exposure of PPX on humoral (PFC & HA) and cellular (DTH) responses, and also monitored T-Cell subtypes u...

Objective(s):Gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. In this study, an attempt was made to evaluate the immunomodulatory potential of gemifloxacin in male swiss albino mice in vivo. Materials and Methods: Three doses of gemifloxacin 25 mg/kg, 50 mg/kg and 75 mg/kg were used intraperitoneally (IP) for the evaluation ...