Introduction: Pigeon Breeder’s Pneumonitis (PBP) results due to a complex pathophysiology that includes exposure avian antigens. Susceptibility has been linked human leukocyte antigen (HLA) class II, though consensus not reached. The goal of this systematic review is further elucidate the association between PBP and HLA-DR subtypes.

abstract background ulcerative colitis (uc) is characterized by recurrent episodes of inflammation limited to the mucosal layer of the colon. calprotectin is a zinc and calcium binding protein derived from neutrophils and monocytes. it is easily detectable in tissue samples, body fluids, and stools, which makes it a potentially valuable marker of inflammation. the aim of the current study is to...

The killing activity of natural killer cells is largely regulated by the binding of class I human leukocyte antigen cognate ligands to killer cell immunoglobulin - like receptor proteins. The killer cell immunoglobulin - like receptor gene - complex contains genes that activate and others that inhibit the killing state of natural killer cells depending on the binding of specific human leukocyte...

INTRODUCTION Hyperacute rejection may be prevented by avoiding the transplantation of kidneys into patients with pre-existing anti-donor Class I human leukocyte antigen antibodies. However, the role of anti-donor-Class II-human leukocyte antigen-DQ antibodies is not established. The question is ever more relevant as more sensitive cross-matching techniques detect many additional antibodies duri...

Background: Human leukocyte antigen (HLA) class II has shown potential in determining prognosis, understanding medication reactions, and predicting onset of Graves’ disease. The aim this study is to further investigate the association between disease HLA II, specifically HLA-DQ HLA-DR, via meta-analysis find HLAs that can be examined for prognostic reasons.

BACKGROUND Successful transfusion of platelet refractory patients is a challenge. Many potential donors are needed to sustain human leukocyte antigen matched-platelet transfusion programs because of the different types of antigens and the constant needs of these patients. For a highly mixed population such as the Brazilian population, the pool size required to provide adequate platelet support ...