Tumor-related vessel length (TVE) was quantified as the number of pixels skeletonized tumor vessels on ultrafast dynamic contrast-enhanced MRI (UF-DCE MRI). The association between TVE and breast cancer subtypes investigated. Invasive presenting with human epidermal growth factor receptor 2 (HER2) associated increased tumor-related length.

OBJECTIVE In vitro chemotherapy response assays are not widely accepted in making decisions regarding cytotoxic drugs. To evaluate the usefulness of chemotherapy response assays in breast cancer, we compared the chemotherapy response assay results according to subtypes. Human epidermal growth factor receptor-2 and Ki67 associated with chemosensitivity were also analyzed. METHODS Four hundred ...

Pyruvate kinase type M2, which is expressed in multiple tumor cell types and plays a key role in aerobic glycolysis, also has nonglycolytic functions and can regulate transcription and cell proliferation. The results of this study show that epidermal growth factor receptor activation induces pyruvate kinase type M2 nuclear translocation. To further determine the relationship between pyruvate ki...

To clarify association of epidermal growth factor receptor, human receptor 2 with prognosis colorectal cancer under FOLFOX chemotherapy. A total 108 patients chemotherapy in the hospital from October 2017 to 2019 were chosen as research subjects. The baseline data recorded before treatment and levels serum tumor markers carcino embryonic antigen carbohydrate 125 measured recorded. After 6 cours...

results a low adc value was associated with lymph node metastasis (p < 0.01) and with high ki-67 protein levels (p = 0.03). there were no significant differences in the adc values among the histological grade (p = 0.48), molecular subtype (p = 0.51), tumor size (p = 0.46), and p53 protein level (p = 0.62). conclusion the pre-operative use of the 3.0 tesla dwi could provide information about the...

Objective(s): Our previous study showed that a newly designed tracer radioiodinated 6-(3-morpholinopropoxy)-7-ethoxy-4-(3'-iodophenoxy)quinazoline ([125I]PYK) is promising for the evaluation of the epidermal growth factor receptor (EGFR) status and prediction of gefitinib treatment of non-small cell lung cancer. EGFR is over-expressed and mutated also in glioblastoma. In the present study, the ...