BACKGROUND Brucellosis is a zoonosis of veterinary, public health and economic significance in most developing countries. Human brucellosis is a severely debilitating disease that requires prolonged treatment with a combination of antibiotics. The disease can result in permanent and disabling sequel, and results in considerable medical expenses in addition to loss of income due to loss of worki...

Brucellosis is an urgent infectious disease of livestock and wild animals and the commonest human zoonosis. Diagnosis of brucellosis is rather complicated and it has to be obligatorily confirmed by laboratory testing. Direct bacteriological and molecular methods and indirect serological tests are used for brucellosis diagnostics. The choice of the diagnostic tools depends on the overall epidemi...

Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors. Acquired immunity to brucellosis has been studied through observations of naturally infected hosts (cattle, goats), mouse models (mice), and human infection. Even though Brucella spp....

LTHOUGH it has been known for many years that brucella may invade the bone marrow, there is a paucity of precise information concerning the pathological changes that take place in this organ as a result of brucellosis. The available descriptions have resulted from a study of human material obtained at autopsy and investigations of tissues from experimentally infected animals. The present study ...

Brucellosis is an abortifacient zoonotic disease which remains prominent in third world countries like Nepal. Brucellosis possess a public health concern, the incidences of which in livestocks can present substantial economic and health burdens for herders and health professionals. In Nepal, several cases of bovine including human brucellosis have been reported. This paper aims to evaluate the ...

BACKGROUND Human brucellosis has a serious medical impact worldwide, and its eradication poses major difficulties. Although human brucellosis is relatively rare in the United States (approximately 100 cases per year), there is concern that this disease is largely underdiagnosed and underreported. Additionally, immigrants from endemic areas are arriving to this country, and Brucella species are ...

Over the past 10 years more than 700 cases of brucellosis have been reported in Kosovo, which is heavily oriented towards agriculture and animal husbandry. Here, brucellosis is still endemic and represents an uncontrolled public health problem. Human brucellosis may present with a broad spectrum of clinical manifestations; among them, vascular complications are uncommon. Hereby we describe the ...

BACKGROUND After the transition from socialism to a market economy in 1990, human brucellosis re-emerged in Mongolia. The aim of our study was to estimate a representative seroprevalence of Brucella spp. and to determine risk factors for brucellosis seropositivity among rural people. METHODS A cross-sectional study with multistage random selection was conducted in eight provinces of Mongolia....

Brucellosis is a highly contagious zoonosis affecting livestock and human beings. The human disease lacks pathognomonic symptoms and laboratory tests are essential for its diagnosis. However, most tests are difficult to implement in the areas and countries were brucellosis is endemic. Here, we compared the simple and cheap Rose Bengal Test (RBT) with serum agglutination, Coombs, competitive ELI...

Dear Editor, The recent report on “human brucellosis” is very interesting (1). Indeed, brucellosis is a zoonosis. As noted by Roushan et al., this disease can be seen in “the Mediterranean areas, the south and the center of America, Africa, Asia, Arab peninsula, Indian subcontinent and the Middle East (1).” Mir et al. noted that this infection should be included in the list of differential diag...