Planned as Shanghai's new port, Yangshan is currently expanding its roles as transhipment hub and integrated logistics/industrial center in the Asia-Pacific region. This paper examines the impact of the emergence of Yangshan on the spatial pattern of the Yangtze River Delta since the 1970s, with reference to existing port system spatial evolutionary models. While this emergence confirms the tre...

the existing works considering the flow-based discount factor in the hub and spoke problems, assume that increasing the amount of flow passing through each edge of network continuously decreases the unit flow transportation cost. although a higher volume of flow allows for using wider links and consequently cheaper transportation, but the unit of flow enjoys more discounts, quite like replacing...

in this paper, a robust model presented is developed for hub covering flow problem in which hubs have capacity. this problem has two objective functions converting to a single-objective problem by using weighting method. firstly, the problem will be formulated in a certain case. then, by considering the demand as a non-random variable, it will be modeled by robust optimization. finally, by usin...

The aim of this study was to identify differentially expressed genes (DEGs) in renal medullary hypertension and reveal their pathogenic mechanisms. We downloaded the gene expression profile of GSE28360 from the Gene Expression Omnibus database. The profile included 14 samples (5 normal and 9 hypertension). The DEGs in normal and disease samples were distinguished with a false-discovery rate thr...

The goals of hub location problems are finding the location of hub facilities and determining the allocation of non-hub nodes to these located hubs. In this work, we discuss the multi-modal single allocation capacitated p-hub covering problem over fully interconnected hub networks. Therefore, we provide a formulation to this end. The purpose of our model is to find the location of hubs and the ...

BACKGROUND EEG studies have shown that patients with Alzheimer's disease (AD) have weaker functional connectivity than controls, especially in higher frequency bands. Furthermore, active regions seem more prone to AD pathology. How functional connectivity is affected in AD subgroups of disease severity and how network hubs (highly connected brain areas) change is not known. We compared AD patie...

Abstract Hub-filament systems (HFSs) are potential sites of protocluster and massive star formation, play a key role in mass accumulation. We report JCMT POL-2 850 ? m polarization observations toward the HFS SDC13. detect an organized magnetic field near hub center with cloud-scale “U-shape” morphology following western edge hub. Together larger-scale APEX 13 CO PLANCK data, we find that SDC13...