نتایج جستجو برای: htlv 1 proviral load

تعداد نتایج: 2872681  

Journal: :Blood 2010
Masako Iwanaga Toshiki Watanabe Atae Utsunomiya Akihiko Okayama Kaoru Uchimaru Ki-Ryang Koh Masao Ogata Hiroshi Kikuchi Yasuko Sagara Kimiharu Uozumi Manabu Mochizuki Kunihiro Tsukasaki Yoshio Saburi Masaomi Yamamura Junji Tanaka Yukiyoshi Moriuchi Shigeo Hino Shimeru Kamihira Kazunari Yamaguchi

Definitive risk factors for the development of adult T-cell leukemia (ATL) among asymptomatic human T-cell leukemia virus type I (HTLV-1) carriers remain unclear. Recently, HTLV-1 proviral loads have been evaluated as important predictors of ATL, but a few small prospective studies have been conducted. We prospectively evaluated 1218 asymptomatic HTLV-1 carriers (426 males and 792 females) who ...

Journal: :iranian journal of basic medical sciences 0
hossein rahimi hematology department, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran seyyed abdolrahim rezaee immunology research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran narges valizade inflammation and inflammatory diseases research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran rosita vakili inflammation and inflammatory diseases research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran houshang rafatpanah inflammation and inflammatory diseases research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran

objective(s): htlv-i and hiv virus quantification is an important marker for assessment of virus activities. since there is a direct relationship between the number of virus and disease progression, htlv- i and hiv co-infection might have an influence on the development of viral associated diseases, thus, viral replication of these viruses and co-infection were evaluated.   materials and method...

Journal: :Journal of neurovirology 2000
T Matsuzaki M Nakagawa M Nagai Y Nobuhara K Usuku I Higuchi K Takahashi T Moritoyo K Arimura S Izumo S Akiba M Osame

To clarify the existence of HAM/TSP presenting amyotrophic lateral sclerosis (ALS)-like manifestations, we assayed HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) in 15 patients with anti-HTLV-I antibody in serum and ALS-like manifestations (upper motor neuron involvement in at least one region and lower motor neuron involvement in at least two limbs) by quantitative PCR, and ...

2013
Jordana Grazziela Alves Coelho-dos-Reis Livia Passos Mariana Costa Duarte Marcelo Grossi Araújo Ana Carolina Campi-Azevedo Andréa Teixeira-Carvalho Vanessa Peruhype-Magalhães Bruno Caetano Trindade Raquel dos Santos Dias Marina Lobato Martins Anna Barbara de Freitas Carneiro-Proietti Antônio Carlos Guedes Denise Utsch Gonçalves Olindo Assis Martins-Filho

In the present study, the frequency, the activation and the cytokine and chemokine profile of HTLV-1 carriers with or without dermatological lesions were thoroughly described and compared. The results indicated that HTLV-1-infected patients with dermatological lesions have distinct frequency and activation status when compared to asymptomatic carriers. Alterations in the CD4(+)HLA-DR(+), CD8(+)...

Journal: :Antiviral therapy 2011
Natsumi Araya Katsunori Takahashi Tomoo Sato Tatsufumi Nakamura Chika Sawa Daisuke Hasegawa Hitoshi Ando Satoko Aratani Naoko Yagishita Ryoji Fujii Hiroshi Oka Kusuki Nishioka Toshihiro Nakajima Naoki Mori Yoshihisa Yamano

BACKGROUND Human T-lymphotropic virus type-1 (HTLV-1) is a human retrovirus that causes HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia (ATL). A higher viral load in individuals with HTLV-1 infection increases their risk of developing HAM/TSP and ATL. Moreover, the high proviral load is associated with the clinical progression of HAM/TSP. Reduction...

Journal: :مجله علوم اعصاب شفای خاتم 0
alireza hoseini a. student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran b. neuroscience department, mashhad university of medical sciences, mashhad, iran amirreza memari a. student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran b. neuroscience department, mashhad university of medical sciences, mashhad, iran houshang rafatpanah inflammation and inflammatory diseases research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran hamid reza rahimi department of modern sciences and technologies, faculty of medicine, mashhad university of medical sciences, mashhad, iran

human t-lymphotropic virus type i (htlv-1) is an endemic virus in iran and other regions that is associated with multiple diseases including adult t-cell leukemia/ lymphoma and a chronic debilitating neuroinflammatory disease, htlv-1-associated myelopathy/tropical spastic paraparesis (ham/tsp). ham/tsp is seen in approximately 2% of htlv-1-infected people with symptoms such as back pain, weakne...

Journal: :The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2012
Viviana Nilla Olavarria Alline do Nascimento Gomes Ramon de Almeida Kruschewsky Bernardo Galvão-Castro Maria Fernanda Rios Grassi

INTRODUCTION Variations in human T cell lymphotropic virus type 1 (HTLV-1) proviral load (PVL) in infected individuals over time are not well understood. OBJECTIVE To evaluate the evolution of proviral load in asymptomatic individuals and HAM/TSP patients in order to help determine periodicity for measuring proviral load. METHODS A group of 104 HTLV-1 infected patients, followed at the HTLV...

AliReza Hoseini, Amirreza Memari, Hamid Reza Rahimi, Houshang Rafatpanah,

Human T-lymphotropic virus type I (HTLV-1) is an endemic virus in Iran and other regions that is associated with multiple diseases including adult T-cell leukemia/ lymphoma and a chronic debilitating neuroinflammatory disease, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is seen in approximately 2% of HTLV-1-infected people with symptoms such as back pain, weakne...

Journal: :iranian journal of basic medical sciences 0
rosita vakili htlv-i foundation, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran faezeh sabet htlv-i foundation, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran sanaz ahmadi ghezeldasht centre of pathological and medical diagnostic services, iranian academic centre for education, culture & research (acecr), mashhad branch, mashhad, iran reza boostani department of neurology, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran houshang rafatpanah inflammation and inflammatory diseases research centre, school of medicine, mashhad university of medical sciences, mashhad, iran ali shamsian centre of pathological and medical diagnostic services, iranian academic centre for education, culture & research (acecr), mashhad branch, mashhad, iran

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Journal: :BMC Infectious Diseases 2021

Abstract Background Human T-lymphotropic virus 1 (HTLV-1) is etiologically associated with the chronic inflammatory neurodegenerative disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) Annexin A1 (AnxA1) an anti-inflammatory protein proposed neuroprotective and anti-neuroinflammatory functions. We hypothesized that ANXA1 gene expression may be dysregulated in HTLV-1-inf...

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