Stromal cells from DBA/2 mouse bone marrow have been shown to be susceptible to cytotoxicity induced by several redox-active metabolites of benzene, including hydroquinone (HQ). Treatment with HQ also alters the composition of stromal cell populations by preferentially killing stromal macrophages compared to stromal fibroblasts. This cytotoxicity can be prevented by 1,2-dithiole-3-thione (DTT) ...

The aim of this manuscript is to present a new concept of hesitant q-rung orthopair fuzzy sets (Hq-ROFSs) by combining the concept of the q-ROFSs as well as Hesitant fuzzy sets. The proposed concept is the generalization of the fuzzy sets, intuitionistic fuzzy sets, hesitant fuzzy sets, and Pythagorean fuzzy sets as well as intuitionistic hesitant fuzzy sets (IHFSs) and hesitant Pythagorean fuz...

BACKGROUND Allelopathic functions of plant-released chemicals are often studied through growth bioassays assuming that these chemicals will directly impact plant growth. This overlooks the role of soil factors in mediating allelopathic activities of chemicals, particularly non-volatiles. Here we examined the allelopathic potential of 8-hydroxyquinoline (HQ), a chemical reported to be exuded fro...

Radix Astragali (RA), known as "Huangqi" in China, is one of the most popular herbal medicines known worldwide to reinforce "Qi". RA is traditionally prepared from the dried roots of Astragalus membranaceus (MJHQ) and A. membranaceus var. mongholicus (MGHQ). Radix Hedysari is named "Hongqi" (HQ), which is similar to RA. We assessed and compared the chemical constituents and bioactivity of RA an...

Three experiments were conducted to evaluate the effects of diet and monensin on performance, digestibility, and methane production in steers fed forage-based diets. In Exp. 1, 72 individually fed steers (300 ± 25 kg) were used in a randomized block design arranged as 2 separate 2 × 2 factorials with two common treatments, thus 6 diets were fed with 12 steers per treatment. Factors included hig...

Hydroquinone (HQ) has been reported to produce chromosomal effects in some in vivo and in vitro animal models. Its potential for inducing similar effects in human lymphocytes is less clear. The purpose of this study was to examine human lymphocytes treated with HQ for the presence of chromosomal anomalies, using an accepted assay for micronuclei. In addition, the stability of HQ in culture medi...

BACKGROUND Self-administered computer-assisted blood donor screening strategies may elicit more accurate responses and improve the screening process. METHODS Randomized crossover trial comparing responses to questions on a computerized hand-held tool (HealthQuiz, or HQ), to responses on the standard written instrument (Donor Health Assessment Questionnaire, or DHAQ). Randomly selected donors ...

BACKGROUND AND AIMS AIF (apoptosis inducing factor) is a flavin and NADH containing protein located within mitochondria required for optimal function of the respiratory chain. AIF may function as an antioxidant within mitochondria, yet when released from mitochondria it activates caspase-independent cell death. The Harlequin (Hq) mouse has a markedly reduced content of AIF, providing an experim...

Cytochrome P450 (CYP) 2E1 was the most efficient CYP enzyme that oxidized benzene to soluble and covalently bound metabolites in rat and human liver microsomes. The covalent binding was due mostly to the formation of benzoquinone (BQ), the oxidation product of hydroquinone (HQ), and was inversely related to the formation of soluble metabolites. In rats, inhalation of benzene (4 mg/liter of air)...