نتایج جستجو برای: homotaurine

تعداد نتایج: 37  

2011
Paul S. Aisen Serge Gauthier Steven H. Ferris Daniel Saumier Denis Haine Denis Garceau Anh Duong Joyce Suhy Joonmi Oh Wan C. Lau John Sampalis

INTRODUCTION The aim of the study was to assess the clinical efficacy, safety, and disease-modification effects of tramiprosate (homotaurine, ALZHEMED(TM)) in mild-to-moderate Alzheimer's disease (AD). MATERIAL AND METHODS Double-blind, placebo-controlled, randomized trial in 67 clinical centres across North America. Patients aged ≥ 50 years, with mild-to-moderate AD (Mini-Mental State Examin...

2012
Katie Witkiewitz Kimber Saville Kacie Hamreus

Acamprosate, or N-acetyl homotaurine, is an N-methyl-D-aspartate receptor modulator approved by the Food and Drug Administration (FDA) as a pharmacological treatment for alcohol dependence. The exact mechanism of action of acamprosate is still under investigation, but the drug appears to work by promoting a balance between the excitatory and inhibitory neurotransmitters, glutamate and gamma-ami...

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