to identify the species of sea cucumbers belong to holothuroidea in the intertidal zones of chabahar bay, field studies were conducted during one year from november 2008 to september 2009. the area of study was located at the farthest end of southeast of iran in province of sistan and balouchestan between 25°16́́ 61̋ and 25°22́ 47 ̋ north, and between 60°39́ 90 ̋ and 60°24́ 38 ̋ east. 5 sampling station...

Background: Holothuroids (sea cucumbers) are members of the phylum echinodermata, which produce saponins. Saponins exhibit a wide spectrum of pharmacological and biological activities. In this study, we isolated the crude saponins from the body wall of the dominant Iranian species of sea cucumber, Holothuria leucospilota (H. leucospilota). The purpose of this study was to confirm the presence o...

Background: Pharmaceutical industries around the world are struggling for finding new approaches to fight cancer and many researchers are involved in this process to find new drug candidates. Aims: The current study aimed at investigating the new marine natural products with anticancer potential from the three Persian Gulf Holothuria sea cucumbers. <st...

sphingolipids (GSLs) from echinoderms, a series of studies on the isolation and structural elucidation of the GSLs from sea cucumber species have been performed in our laboratory. In the study of the GSLs of the sea cucumber Holothuria pervicax, we reported the isolation and structure of ten glucocerebrosides revealing a very close resemblance in structure. However, all these compounds still ex...

Aquatics are a source of bioactive compounds that these compounds have different properties such as antimicrobial activity. In this study, antibacterial activity of methanol, chloroform and hexane extracts from body wall, gonad and intestine of sea cucumber Holothuria leucospilota was evaluated against Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus. Bioactive compounds of b...