BACKGROUND Holding orders help transition admitted emergency department (ED) patients to hospital beds. OBJECTIVE To describe the effect of ED holding orders. METHODS We conducted a single-site retrospective study of ward admissions from the ED to the hospital internal medicine (HIM) service over 2 years. Patients were classified based on whether the ED did (group 1) or did not (group 2) wr...

Today’s IP network layer provides little to no protection against misconfiguration or malice. Despite some progress in improving the robustness and security of the IP layer, misconfigurations and attacks still occur frequently. We show how a network layer that provides accountability, i.e., the ability to associate each action with the responsible entity, provides a firm foundation for defenses...

Yeast cells are known to actively partition organelles between the mother and bud during division. Mitochondria, for example, are subjected to both retention and ordered movement to ensure that a proper fraction of the organelles end up in each cell after cytokinesis. In the case of peroxisomes, researchers knew that a subset of the organelles moved into the bud in a myosin-dependent manner, bu...

BACKGROUND Recently, the frequency of audit inspections of health services for people with intellectual disability (ID) in the UK has increased, from occasional inquiries to a systematic audit of all services. From 2008, a process of continuous audit 'surveillance' of specialist health services is to be introduced. Similar regimes of inspection are in place for social care services. AIM To ex...