background: cell mediated immunity, especially cytotoxic t cell responses against hiv-1 infection, plays a critical role in controlling viral replication and disease progres-sion. dna vaccine is a novel technology which is known to stimulate strong cellular immune responses. many dna vaccines have been tested for hiv infection but there is still no effective vaccine against this infection. cons...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Safdari R, SeyedAlinaghi S, Mohammadzadeh N, et al. Developing Aysoo: a mobile-based self-management application for people living with HIV. HIV & AIDS Review. International Journal of HIV-Related Problems. 2022;21(1):24-30. doi:10.5114/hivar.2022.113389. APA Safdari, R., SeyedAlinaghi, S., Mohammadzadeh, N., Noor...

Human immunodeficiency virus type 1 (HIV-1) is most notable for its role in directly infecting and killing CD4 T cells the immune system, which can lead to acquisition of Acquired Immunodeficiency Syndrome (AIDS). Currently, there are no cures HIV-1, leaving 37 million people with HIV-1 infections definitive treatment. Researchers working towards developing long-term treatments using CRISPR-Cas...

In an attempt to identify potential new agents that are active against HIV-1, a series of novel pyridopyrimidine-5-carbohydrazide derivatives featuring a substituted benzylidene fragment were designed and synthesized based on the general pharmacophore of HIV-1 integrase inhibitors. The cytotoxicity profiles of these compounds showed no significant toxicity to human cells and they exhibited anti...

Human Immunodeficiency Virus (HIV) infects human by destroying the immune system. The types of HIV strains HIV-1 and HIV-2, among being more prevalent considered deadly. Eventually either leads to disease Acquired Syndrome (AIDS). Traditional medicinal plants have a pivotal role in modern pharmacological process due their rich composition secondary metabolites with significant biological activi...

Disease progression is slower in HIV-2, as compared with HIV-1 infection, accordance low or undetectable plasma viremia at viral setpoint. However, it unclear why most HIV-2 infected individuals are still risk of developing AIDS. To explore if specific host responses linked to HIV disease severity, we have blood gene expression profiles between seronegative and HIV-1, dually HIV-1/HIV-2 individ...

Abstract Background and Aims: The burden of HIV infection and disease continues to be a major global public health concern all over the world. This study was conducted to measure IgG antibody against EBV viral capsid antigen (EBV-VCA IgG), Herpes Simplex Type1, and 2 to determine the seroprevalence of this infection in HIV-positive population. Materials and Methods: A Cross-sectional st...