With the increasing number of documents that are available in digital form, also the number of digital historical documents is increasing (Berkvens, 2001). It cannot be assumed that standard IR systems perform well on historical documents: historical texts differ from modern texts in three ways (Hüning, 1996; Van Der Horst and Marschall, 1989): (a) vocabularies have changed, (b) spelling has ch...

Mutations in the HFE (hemochromatosis) gene cause hereditary hemochromatosis, an iron overload disorder that is hallmarked by excessive accumulation of iron in parenchymal organs. The HFE mutation p.Cys282Tyr is pathologically most relevant and occurs in the Caucasian population with a carrier frequency of up to 1 in 8 in specific European regions. Despite this high prevalence, the mutation cau...

OBJECTIVE Levels of tissue iron contribute to determining diabetes risk, but little is known about the effects of higher iron levels on weight, and on the interaction of weight and iron overload on diabetes risk. Therefore, the effect of iron on body mass index and diabetes in individuals with iron overload from hereditary hemochromatosis (HH), compared to non-HH siblings and historical control...

Introduction: Iron deficiency anemia is recognized as the most prevalent nutrient deficiency in the world and iron supplements, which are prescribed daily in pregnant women for prevention of this anemia, may have unfavorable effects on copper absorption. The purpose of this study was to determine the effects of iron supplementation on serum copper status of pregnant women. Materials and Methods...

Our understanding of the complex aqueous chemistry of iron in natural systems has advanced significantly over recent years. Here we will highlight how new contributions from nanogeoscience combine with conventional aqueous geochemistry to provide a novel view of kinetics in the modern iron biogeochemical cycle, and the evolution of the iron cycle through geologic time. We start by considering t...

AIMS Excess iron has been implicated in the pathogenesis of diabetes and its complications. This study documents the assessment of plasma iron indices and the correlation between transferrin saturation with biochemical and clinical parameters in a cross-sectional survey of 820 patients with diabetes in long-term follow-up in a single clinic. METHODS Plasma iron indices, together with the bioc...

Iron sulfate compounds have been used extensively to produce iron gall ink, a widely used writing ink in the western world from the 12th-20th centuries. Iron gall ink is well known to corrode writing supports, so detection of iron species is important for the preservation of historical artwork and documents. Iron(ii) sulfate readily changes hydration states and oxidizes in ambient conditions, f...

The article deals with the sacred groves of the Balts in Lithuania and presents the linguistic background, the historical documents from the 12th– 18th century, the key folklore motifs of the topic, as well as selected examples of groves. The article also discusses possible relationships between pre-Christian religious traditions connected with the sacred groves and the ones which have survived...