There are continued concerns about endocrine-disrupting chemical effects, and appropriate vertebrate models for assessment of risk are a high priority. Frog tadpoles are very sensitive to environmental substances because of their habitat and the complex processes of metamorphosis regulated by the endocrine system, mainly thyroid hormones. During metamorphosis, marked alteration in hormonal fact...

Abstract Aspirin is one of the most widely used medications globally as an analgesic and antipyretic drug. use antiparasitic against fish parasites has never been tested. The parasite Dactylogyrus considered a serious threat to freshwater aquaculture in relation considerable losses. present study aimed evaluate effect aspirin extensus on Cyprinus carpio alteration gill histopathology. In vitro ...

Sensitive and spatial exploration of the metabolism of tumors at the metabolome level is highly challenging. In this study, we developed an in situ metabolomics method based on ambient mass spectrometry imaging using air flow-assisted desorption electrospray ionization (AFADESI), which can spatially explore the alteration of global metabolites in tissues with high sensitivity. Using this method...

background and objective: smoking can be associated with the decreasing gingival blood flow and epithelial changes. the aim of this study was to evaluate the histopathological changes of gingival epithelium and connective tissue in smokers. methods: the study was case-control. sixty male patients (28 smokers and 32 nonsmokers) suffering chronic periodontitis were participated in the study. peri...

The objective of the study was to evaluate the cardioprotective activity of flax lignan concentrate (FLC) in isoprenalin (ISO) induced cardiotoxicity in rats. Male Wistar rats (200-230 g) were divided into three groups. Group I: control, Group II: isoprenalin, Group III: FLC (500 mg/kg, p.o.) orally for 8 days and in group II and III isoprenalin 5.25 mg/kg, s.c. on day 9 and 8.5 mg/kg on day 10...

Background & Objectives: Oral submucous fibrosis (OSMF) is a condition where excessive deposition of dense collagen fibers occurred in the connective tissue of oral mucosa. An alteration of collagen necessitates an in depth understanding of collagen in oral tissues as no breakthrough studies have been reported. Therefore the aim was to correlate the clinical, functional and histopathol...

background: the aim of the present study was to find the effects of cadmium (cd) on japanese quail on the role of an animal model in order to understand the toxicity of cd in creatures presented, within the environment. methods: one hundred 30-day-old male japanese quails were equally divided into the control group and cd group. the control group received no cd while the cd group was given form...

the modern surgical endodontic treatment is a safe and predictable procedure with high success rate. however, several factors can retard or impede the proper healing process. use of a high speed handpiece during hard tissues management (osteotomy and apical resection) can potentially be one of these factors. formation of metallic debris from the surgical diamond burs, production of necrotic loc...

BACKGROUND T-cell lymphomas involve the testis infrequently, which deserve special attention because of the poor prognosis and the need to make an appropriate diagnosis, which could lead to a better therapeutic strategy. CASE PRESENTATION A 40-year-old man presented with right testicular swelling for past three months. The swelling was painless, hard and rubbery. Testicular ultrasound showed ...