It was with great sadness that the philosophical and ethical communities noted the recent passing of Alan Wertheimer. It is not possible to engage in serious work regarding international research ethics (nor much of political philosophy more broadly) without encountering and wrestling with his careful contributions. He was welcoming of discussion and generous with his intellectual energies. Ong...

Label-free detection of the interaction between hexahistidine-tagged human κ-opioid receptor membrane protein and anti-His antibody is demonstrated in liquid by an optical microelectromechanical system utilizing electromagnetically actuated microresonators. Shift in resonance frequency due to accretion of mass on the sensitive surface of microresonators is monitored via an integrated optical re...

Introduction: Medical claim is one of the most concerning subjects for both patients and physicians. In addition, it has lots of financial and nonfinancial costs for health care systems. To define the number and causes of medical claims against dentists of Rasht since 2006 till 2011in Guilan medical council. Materials and Methods: A retrospective cross - sectional study was performed since 200...

We evaluate the ability of hexahistidine (His6) tags on peptide and protein substrates to recruit deoxyribozymes for modifying those substrates. For two different deoxyribozymes, one that creates tyrosine-RNA nucleopeptides and another that phosphorylates tyrosine side chains, we find substantial improvements in yield, kobs, and Km for peptide substrates due to recruiting by His6/Cu(2+). Howeve...

We present a molecular theory to study the adsorption of different species within pH-sensitive hydrogel nanofilms. The theoretical framework allows for a molecular-level description of all the components of the system, and it explicitly accounts for the acid-base equilibrium. We concentrate on the adsorption of hexahistidine, one of the most widely used tags in bio-related systems, particularly...

In this translation, Watsuji Tetsurō sets out to clarify that which is entailed by “national character”. his analysis of idea, critically analyses the Marxist interpretation from perspective Martin Heidegger. After articulating Heidegger’s concept being-there [Dasein], then criticizes approach in three regards. Firstly, questions whether most accessible way encountering things world through con...

this article examines the mu‘tazilite qādī ‘abd al-jabbār’s views on the denotation of miracles according to his own particular methodology. despite his acceptance of the celebrated method of the theologians in the denotation of miracles with respect to the authenticity of prophets, i.e., resorting to divine wisdom, qādī ‘abd al-jabbār instead proposed the issue within the structure of conven...

u. t. place claims that philosophical problems concerning the true nature of mind-brain relationship disappears or is settled adhering to materialism, especially type identity theory of mind. he takes above claim as a reasonable scientific hypothesis. i shall argue why it is not as he claims. at first, to pave the way for refutation, i will briefly clarify place's approach to the subject i...