The combination of the broad problem searching capabilities of a genetic algorithm with the local maxima location capabilities of a hill climbing algorithm can be a powerful technique for solving classification problems. Producing a number of specialist artificial neural networks, each an expert on one category, can be beneficial when solving problems in which the categories are distinct. This ...

In this paper we analyze the asymptotic properties of the popular distribution tail index estimator by Hill (1975) for dependent, heterogeneous processes. We develop new extremal dependence measures that characterize a massive array of linear, nonlinear, and conditional volatility processes with long or short memory. We prove that the Hill estimator is weakly and uniformly weakly consistent for...

The consistency of the quasi maximum likelihood estimator for random coefficient autoregressive models requires that the coefficient be a non-degenerate random variable. In this paper we propose empirical likelihood methods based on weighted score equations to construct a confidence interval for the coefficient. We do not need to distinguish whether the coefficient is random or deterministic an...

B Full model 4 B.1 Derivation from chemical reactions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 B.2 Non-dimensionalisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 B.3 Empirical alteration of the ”Hill coefficient” . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 B.4 Inducible expression of LuxR/LasR . . . . . . . ....

The Ca2+ sensitivity of myofilaments was compared before and after skinning in the same rat trabeculae at a diastolic sarcomere length of 2.2 to 2.3 microns. Trabeculae from rat right ventricle were loaded with fura-2 salt by iontophoretic microinjection, and [Ca2+]i was determined from the epifluorescence at 510 nm when excited at 340 and 380 nm. Steady-state activation was achieved by stimula...

A study was carried out using 24 upland rice genotypes grown in randomized block design with three replications to estimate genetic variability, correlation and path coefficient analysis. Based on the mean performance, of high grain yield per hill, genotype SHUATS UPR-13 followed by UPR-11 were identified be superior. High phenotypic genotypic variation observed for biological hill number panic...

1. Characterization of P2X receptors on neurons of guinea-pig superior cervical ganglion (SCG) has been carried out using a whole-cell voltage-clamp technique. 2. Application of ATP and alpha,beta-methylene ATP (alphabeta-MeATP) produced fast activating inward currents, which desensitized slowly. The maximum response to alphabeta-MeATP was 36 +/- 23 % (range 0.1-100 %) of that evoked by ATP in ...

The calf uterine estrogen receptor showed positive cooperativity of [3H]estradiol equilibrium binding; the Scatchard plot was convex and the Hill coefficient was 1.69 +/- 0.021 (n = 14). The effects of the estrogenic antagonists, zuclomiphene (cis-2-(p-[2-chloro-1,2-diphenylvinyl]phenoxy)triethylamine citrate) and enclomiphene (trans-23-(p-[2-chloro-1,2-diphenylvinyl]phenoxy)triethylamine citra...