نتایج جستجو برای: high dose interferon
تعداد نتایج: 2344472 فیلتر نتایج به سال:
BACKGROUND The optimal treatment for hepatitis C patients unresponsive to interferon is unclear. High-dose induction interferon may enhance early viral clearance, whilst ribavirin reduces relapse; in combination, they may improve sustained virological response rates. AIM To compare the efficacy and safety of re-treatment with interferon induction, with or without ribavirin, in interferon non-...
Background. Current treatment of chronic hepatitis C with pegylated interferon and ribavirin has the ability to eliminate viral infection in about half of the patients treated. Therapeutic options, for those with remaining chronic hepatitis, will remain limited until novel antivirals become available in the future. Consensus interferon is currently available and has demonstrated clinical effica...
Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in Russian Federation, its has not been studied before. The aim this study was to determine interferon drugs, with without it. included cytotoxicity assays preparations, when stored according instructions at 2–8°C, after 1 month storage temper...
objective: acute inflammatory demyelinating peripheral neuropathy (guillain-barre-syndrome) is by far the most common cause of immune-medicated peripheral nervous system disease in children; with the near disappearance of poliomyelitis, gbs is responsible for the great majority of cases of acute flaccid paralysis. so far, in several controlled studies, corticosteroids, plasmapheresis and ivig h...
Hanneke C. Kluin-Nelemans, Georgina Buck, Saskia le Cessie, Sue Richards, H. Berna Beverloo, J.H. Frederik Falkenburg, Tim Littlewood, Petra Muus, David Bareford, Hans van der Lelie, Anthony R Green, Klaas J. Roozendaal, Alison E Milne, Claire S. Chapman and Patricia Shepherd on behalf of the CML Working Group of the NCRI Adult Leukaemia Working Party and the HOVON trials group. Dept. Hematolog...
BACKGROUND The efficacy of re-treating genotype I hepatitis C virus (HCV) patients who failed combination therapy with interferon/pegylated interferon (PEG-IFN) and ribavirin remains unclear. AIMS To quantify sustained virological response (SVR) rates with different re-treatment regimens through meta-analysis of randomized controlled trials (RCTs). METHODS Randomized controlled trials of ge...
Introduction: Based on data from recent trials, peginterferon and ribavirin combination therapy is the standard of care in treating patients with chronic HCV infection, but because of high costs, many patients may deprive from treatment. Methods: We conducted a clinical trial on HCV patients in Yazd in gastroenterology clinic. Thirty patients received conventional subcutaneous interferon alf...
An extensive Phase I evaluation of human lymphoblastoid interferon has been completed which, in addition to describing its clinical and pharmacological effects, emphasized a broad-scale evaluation of the immune response as a function of interferon dosage. Dose-limiting toxicity was generally due to constitutional symptoms which are remarkably similar to those produced by influenza, although tra...
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