Before setting off on a holiday, particularly of the adventurous kind, it is vital to obtain appropriate medical advice to ensure a safe trip. However there are concerns that this need is not being adequately met. In this comment, Irmgard Bauer from James Cook University, Australia, discusses where travel medicine is failing and what can be done about it, in the context of her recent observatio...

Many physicians are surprised to learn how many people live, work, and play at high altitude. Some 140 million persons reside at altitudes over 2500 m, mainly in North, Central, and South America; Asia; and eastern Africa (1). Increasingly, people are moving to work at high altitude. For example, there are telescopes at altitudes over 5000 m (2) and mines at over 4500 m (3), and the Golmud–Lhas...

To investigate the influence of hypoxia during the early stage of incubation on embryonic developmentand hatching events, and consequently on incidence of ascites in broiler chickens, one thousand fertile eggswere incubated in two commercial incubators. Half the eggs were incubated in a low altitude incubator untilhatched. The second half were incubated in a high altitude incubator until day 10...

Any work activity performed at elevations over 3,000 m above sea level is considered as work at high altitude. The changing environmental conditions result in an adaptation of the human organism, mainly due to a reduced partial pressure of oxygen in the air and a proportional decrease in barometric pressure. We carried out a systematic review of the scientific literature in this field so as to ...

the purpose of this investigation was to assess the effect of captopril on both systemic (p.a) and pulmonary arterial pressures (ppa) in patients with high-altitude pulmonary hypertension (haph). seventeen patients (mean age 44±6.8 years) with haph and mild to moderate systemic arterial hypertension were included in the study. all patients underwent right heart catheterization with measurements...

to investigate the influence of hypoxia during the early stage of incubation on embryonic developmentand hatching events, and consequently on incidence of ascites in broiler chickens, one thousand fertile eggswere incubated in two commercial incubators. half the eggs were incubated in a low altitude incubator untilhatched. the second half were incubated in a high altitude incubator until day 10...

Colleen Glyde Julian, Marcelino Gonzales, Armando Rodriguez, Diva Bellido, Carlos Salinas Salmon, Anne Ladenburger, Lindsay Reardon, Enrique Vargas, and Lorna G. Moore Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado; Bolivian Institute of High Altitude Biology, La Paz, Bolivia; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah;...