Hexane, ethanol and aqueous extracts and fractions from leaves of Pouteria torta (Mart.) Radlk (Sapotaceae), a perennial tree, widespread in the Brazilian Cerrado, were tested for cytotoxicity with the Artemia salina toxicity model. Only the aqueous crude extract and the MeCN: CHCl3 fraction of the ethanol extract presented toxicity (0.28 mg/mL and 0.27mg/mL, respectively). Lupeol acetate was i...

Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-he...

The extracts of Chinesc red ant formica aquilonia were screened fbr cytotoxicity, antioxidation and antiinfiammatory properties, prolyl oligopeptidase (POP) inhibition, and the effect on the catecholaniinc secretion, Dried ants were successively extracted with hexane, ethyl acetate, aqueous acetone and distilled water, Both the hexane and ethyl acetate extracts exhibited a high level of POP inh...

Hexane, chloroform, ethyl acetate and methanol extracts of Strychnos nux-vomica Linn. (Family: Loganiaceae) and Semecarpus anacardium Linn. (Family: Anacardiaceae) were incorporated in semi-synthetic diet at 0.5, 1.0, 1.5 and 2% concentrations. Screened for antifeedant, larvicidal, pupicidal and adult malformation activities against Helicoverpa armigera (Lepidoptera: Noctuidae). The chloroform ...

BACKGROUND Costus speciosus (Koen ex.Retz.) Sm (Costaceae) is an Indian ornamental plant which has long been used medicinally in traditional systems of medicine. The plant has been found to possess diverse pharmacological activities. Rhizomes are used to treat pneumonia, rheumatism, dropsy, urinary diseases, jaundice, skin diseases and leaves are used to treat mental disorders. METHOD Antibac...

Lack of data on safety of herbal medicines have endangered human health and life. The present study evaluated the genotoxic and mutagenic effect of Kalanchoe laciniata to access the safety and usefulness of the medicinal plant. Aqua-methanolic and n-hexane extracts of K. laciniata were evaluated for the genotoxic potential using Ames assay and cytotoxicity was evaluated using MTT assay. Ames as...

Background: Clinacanthus nutans (C.nutans) is a plant consumed as a cancer treatment in tropical Asia. Despite the availability of numerous anecdotal reports, evaluation of active anticancer effects has remained elusive. Therefore we here examined antiproliferative, reactive oxygen species (ROS)-inducing and apoptosis mechanisms of whole plant extracts in different cancer cell lines. Methods: A...

Lupeol (1), epilupeol (2) and β-sitosterol (3) were isolated from the n-hexane and the carbon tetrachloride soluble fraction of a methanol extract of the leaves of Phoenix paludosa Roxb. The n-hexane, carbon tetrachloride and chloroform soluble materials from the concentrated methanol extract were subjected to antimicrobial screening and brine shrimp lethality bioassay. All of the partitionates...

Constituents from Polyalthia cerasoides, stem bark methanol extract, were previously documented. This study reports the first isolation of bioactive N-(4-hydroxy-β-phenethyl)-4-hydroxycinnamide (1) from ethyl acetate extract of the plant species including stigmasterol and a mixture of triterpenes from hexane and dichloromethane extracts. Trace essential elements were found in the hexane extract...

Objective: Our objective of this research work was to investigate antimicrobial activity of five species of traditionally used medicinal plants namely Adhatoda vasica, Artemisia annua, Cordia oblique, Croton bonplandianum and Euphorbia milli against different strains of bacteria and fungi which are known to cause various types of infectious diseases. Methods: Organic extracts of these plants le...