نتایج جستجو برای: heterozygote

تعداد نتایج: 22757  

ژورنال: پژوهش در پزشکی 2004
اکرم نریمانی, , , Derakhshan F, سروین پیمان, , سید جواد میرحسنی مقدم, , فرامرز درخشان, , فرناز تقی زاده, , محمدرضا زالی, , نسترن نوروزی, ,

Background : Familial Mediterranean fever (FMF) is an autosomal recessive disease, which is characterized by recurrent short episodes of inflammation in serous membranes. It is most prevalent in Western Mediterranean population. MEFV is the only gene currently known to be associated with this disease. Previous studies revealed that 6% of Iranian Jewish residents in Israel were carriers of MEFV ...

Journal: :Haematologica 2005
Maria Celeste Bento Ko Tung Chang Yongli Guan Enli Liu Gabriela Caldas Richard A Gatti Josef T Prchal

We report on five Caucasian patients with congenital polycythemia and mutations of the von Hipple-Lindau (VHL) gene: a compound heterozygote for the novel exon 1 (VHL 235C->T) and previously reported VHL 562C->G mutations; three homozygotes for Chuvash VHL 598C->T mutation; and a heterozygote for VHL 523->G mutation who also has ataxia-telangiectasia; a rare autosomal disease of childhood onset.

2012
Andreas Gal

About 60-70 % of the heterozygotes of X-linked hypohidrotic ectodermal dysplasia (XLHED) show some clinical manifestations of the disease. Dental abnormalities are key diagnostic features and can be best evaluated at a young age. Compared to controls, carriers have a significantly higher frequency of agenesis of permanent teeth with persistence of deciduous teeth, small teeth resulting in gaps ...

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