Bilateral mesiotemporal hyperintensity on T2-weighted and fluid-attenuated inversion recovery MR images of a patient with a clinical syndrome of encephalitis is considered to be a classic finding for herpes simplex virus infection. We report a case of neurosyphilis with identical MR imaging abnormalities and a similar clinical presentation. Because syphilis is not routinely tested for, awarenes...

We report on a 12-year-old boy with herpes simplex encephalitis, in whom a severe localised skin reaction developed following the infusion of intravenous acyclovir. Oral valaciclovir was given as continuation therapy to complete the 3-week course of antiviral treatment and resulted in complete recovery without side effects. This report illustrates the advantage of using the polymerase chain rea...

The selective destruction of temporal and frontal lobe structures by herpes simplex encephalitis has been explained as a consequence of the proximity of those regions to the point of entry of the virus in the encephalon, through olfactory pathways or meningeal branches of the trigeminal nerves. An alternative hypothesis is presented: that the encephalitis is due to a special affinity of the her...

INTRODUCTION Histopathologically, herpes simplex virus type 1 causes hemorrhagic necrosis. Overt hemorrhage is infrequent in herpes simplex virus encephalitis but can lead to poor outcomes. This report describes a successfully treated case of herpes simplex virus encephalitis associated with subarachnoid bleeding in which real-time polymerase chain reaction was useful for diagnosis. CASE PRES...

Herpes simplex encephalitis (HSE) is an acute or subacute sporadic encephalitic illness. It has a predilection for the medial temporal lobes, the orbital surface of the frontal lobes, and subcortical structures such as the hippocampus. Sequelae may include seizures and neuropsychological impairment. The present case study involves a 66-year old, retired, Caucasian male diagnosed with herpes sim...

In this paper seven cases of severe viral encephalitis seen over a four year period at the Princes Alexandria Hospital, Brisbane, are presented. Four of these cases were proven cases of Herpes simplex encephalitis on the basis of viral culture, and three were probable cases of Herpes simplex encephalitis on the basis of rising serum antibody titres. A summary of the clinical aspects and laborat...

Herpes simplex virus (HSV) encephalitis is the fulminant necrotizing viral encephalitis associated with high mortality and morbidity. Here we report a case of HSV encephalitis mimicking cerebral infarction who recovered with intensive intravenous acyclovir therapy.