Dandruff, a clinical condition caused by Malassezia (Pityrosporum) species is of great cosmetic concern all over the world. Dandruff is known to be controlled by fungistatic ingredients in Anti-dandruff shampoos. A comparative study on the efficacy of chemical and herbal anti-dandruff ingredients on ’as is’ basis and their performance in market shampoos was done in vitro against Pityrosporum ov...

BACKGROUND Possible mechanisms of Alzheimer Disease (AD) such as inflammation and oxidative stresses in the brain led us to investigate potential AD therapeutics of Melilotus officinalis, an herbal extract, with possible role as an anti-inflammatory and anti-oxidant agent. Among different genes which had important role in Sporadic AD (SAD), three genes including DAXX, NFkB and VEGF have shown s...

The use of herbal products has increased significantly in recent years. Because these products are not subject to regulation by the Food and Drug Administration and are often used without supervision by a healthcare provider, the indication for and consumption of these supplements is quite variable. Moreover, their use is generally regarded as safe and natural by the lay-public. Unfortunately, ...

The aim of this study is pharmacochemistry of Iranian flora Artemisia sieberi and its antimalarial effects on Plasmodium berghei in vivo. This is the first application of A. sieberi for treatment of murine malaria. A. sieberi were collected at flowering stage from the Khorassan and Semnan provinces of Iran; the aerial parts were air-dried at room temperature and then powdered. The powder was ma...

The objective of this study was to investigate the single dose antioxidant and antidiabetic effect of a herbomineral amino acid extract (HMAA) of Spinacia oleracea on alloxan induced diabetic rats. In the present study, the animals were divided into 6 groups: Group 1 – Normal saline as vehicle –control, Group 2 – Untreated diabetic rats (Alloxan induced), Group 3 – Animals treated with Metformi...

Purpose: Sporadic Alzheimer's disease (AD) accounts for over 95% of cases. Possible mechanisms of AD such as inflammation and oxidative stresses in the brain motivate researchers to follow many therapies which would be effective, especially in the early stages of the disease. IMOD, the herbal extract of R. Canina, T. Vulgare and U. Dioica plant species enriched with selenium, has anti-inflammat...

Objective: The development of modern dosage form such as lozenges associated with an extended period of local remedy with beneficial therapeutic effect was the objective of this study. The polyherbal extract based lozenges include Viola odorata L, Cordialatifolia L, Menthapiperita L., Adhatodavasica, Glycyrrhizaglabra, Piper longum, Hyssopusofficinalis, Alpiniagalangal which is envisioned for c...

semelil is an herbal-based compound which is used for the treatment of chronic wounds, especially diabetic foot ulcers. on the other hand, electrospun nanofibers have many characteristics such as mimicking extracellular matrix structure, efficiency as bacterial barrier, appropriate water vapor transmission rate, and provision of adequate gaseous exchange which make them ideal candidates for wou...

Kaempferia parviflora Wall.ex.Baker is a Thai medicinal herb that has high antioxidant and anti-inflammatory activities. Apoptotic effects of the herbal extract alone and in combination with chemotherapeutic drugs, paclitaxel and camptothecin, were here studied in the human promonocytic leukemic U937 cell line. K. parviflora extract suppressed cell proliferation and decreased cell viability in ...