نتایج جستجو برای: hepatoma cells

تعداد نتایج: 1385970  

Journal: :Oncology reports 2016
Kuo-Shyang Jeng Chi-Juei Jeng Wen-Juei Jeng I-Shyan Sheen Shih-Yun Li Zih-Hang Hung Hsin-I Hsiau Ming-Che Yu Chiung-Fang Chang

Hepatocellular carcinoma (HCC) is a worldwide malignancy with poor prognosis. Liver progenitors or stem cells could be a potential therapy for HCC treatment since they migrate toward tumors. Rat liver epithelial (RLE) cells have both progenitor and stem cell-like properties. Therefore, our study elucidated the therapeutic effect of RLE cells in rat hepatoma cells. RLE cells were isolated from 1...

Journal: :Cancer research 1991
R A Canuto G Muzio M E Biocca M U Dianzani

Tumor cells generally display low lipid peroxidation. A low content of polyunsaturated fatty acids in membrane phospholipids is a possible cause of their decreased susceptibility to lipid peroxidation. To investigate the importance of substrate availability in eliciting lipid peroxidation and to study cell viability in conditions of stimulated lipid peroxidation, AH-130 hepatoma cells were enri...

2006
Rosa A. Canuto Giuliana Muzio Maria E. Biocca Mario U. Dianzani

Tumor cells generally display low lipid peroxidation. A low content of polyunsaturated fatty acids in membrane phospholipids is a possible cause of their decreased susceptibility to lipid peroxidation. To investigate the importance of substrate availability in eliciting lipid peroxidation and to study cell viability in conditions of stimulated lipid peroxidation, AH-130 hepatoma cells were enri...

Journal: :International Journal of Molecular Sciences 2021

Carnosic acid (CA), carnosol (CL) and rosmarinic (RA), components of the herb rosemary, reportedly exert favorable metabolic actions. This study showed that both CA CL, but not RA, induce significant phosphorylation AMP-dependent kinase (AMPK) its downstream acetyl-CoA carboxylase 1 (ACC1) in HepG2 hepatoma cells. Glucose-6-phosphatase (G6PC) phosphoenolpyruvate carboxykinase (PCK1), rate-limit...

2014
Yunhai Dai Xiaopeng Xiong Gang Huang Jianjun Liu Shile Sheng Hongjian Wang Wenxin Qin

A unique bioenergetic feature of cancer, aerobic glycolysis is considered an attractive therapeutic target for cancer therapy. Recently, dichloroacetate (DCA), a small-molecule metabolic modulator, was shown to reverse the glycolytic phenotype, induce reactive oxygen species (ROS) generation, and trigger apoptosis in various tumor cells. In this work, the capacity of DCA to enhance Adriamycin (...

2017
Xuefeng Kan Wanli Zhang Ruxu You Yanfeng Niu Jianrong Guo Jun Xue

BACKGROUND Previous studies showed Scutellaria barbata D. Don extract (SBE) is a potent inhibitor in hepatoma and could improve immune function of hepatoma H22-bearing mice. However, the immunomodulatory function of SBE on the tumor growth of hepatoma remains unclear. This study aimed to investigate the anti-tumor effects of SBE on hepatoma H22-bearing mice and explore the underlying immunomodu...

2014
Yu-Jen Chen Chih-Wen Chi Wen-Chi Su Huey-Lan Huang

Lapatinib, an orally administered small-molecule tyrosine kinase inhibitor targeting epidermal growth factor receptors (EGFR) and Her2/Neu, has been widely accepted in the treatment of breast cancer. In this study, we found that lapatinib induced cytotoxicity in human hepatoma Huh7, HepG2 and HA22T cells. For the mode of cell death, we found lapatinib induced a higher percent of dead cells and ...

2006
Rosa A. Canuto Giuliana Muzio Maria E. Biocca Mario U. Dianzani

Tumor cells generally display low lipid peroxidation. A low content of polyunsaturated fatty acids in membrane phospholipids is a possible cause of their decreased susceptibility to lipid peroxidation. To investigate the importance of substrate availability in eliciting lipid peroxidation and to study cell viability in conditions of stimulated lipid peroxidation, AH-130 hepatoma cells were enri...

Journal: :The Biochemical journal 1972
J Woo D B Cater

1. Rabbit anti-(rat foetal liver) serum, absorbed with adult rat liver cells, decreased the electrophoretic mobility of foetal liver cells by 51% and rat hepatoma cells by 45%, indicating the presence of a foetal-type antigen on the hepatoma cell membrane. 2. The chemical nature of the surface antigen was investigated. Incubation with neuraminidase had no effect on adult liver cells but decreas...

Journal: :Cancer research 1960
H T SHIGEURA C N GORDON

Rapidly proliferating normal and malignant cells had a greater initial rate of amino acid incorporation into mierosomal proteins than did normal cells. The rate of mierosomal protein renewal in Novikoff hepatoma was greater than that of liver cells. The initial rates of amino acid incorporation into hepatoma and liver ribonueleoprotein particles were approximately equal. The soluble fractions o...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید