Rational:Lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) is a rare variant of hepatocellular carcinoma (HCC). To date, few cases have been reported in the literature, and almost no report in analyzing the different features of LEL-HCC. Patient concerns: We describe a 37-year-old female patient with a 32 30mm mass in the right liver. Interventions: Complete surgical resection of the le...

Radiotherapy plays an important role in the treatment of hepatocellular carcinoma (HCC). Cyclin G1 is a novel member cyclin family, and it abnormally expressed HCC. In this study we investigated radiotherapy HCC cells. The expression was silenced by transfection G1-siRNA into HepG2 cells Huh7 cells, mRNA protein measured qRT-PCR Western blot analysis. proliferation analyzed using MTT assay, rad...

Abstract: Background and Aim: To study the antitumor activity of 2-Methoxy-1,4-naphthoquinone (MNQ) against hepatocellular carcinoma (HCC) cells, in an attempt to fill knowledge gap anti-liver cancer with MNQ. Materials Methods: Cell viability presence MNQ was assessed by MTT effect on HepG2 cell cycle flow cytometry. analyze apoptosis its molecular mechanisms, we used a combination Hoechst 333...

[Original]Hepatocellular carcinoma (HCC) is the most common primary neoplasm of liver, which arises from parenchymal cells liver.1 Hepatocellular usually develops in setting chronic background liver disease, such as cirrhosis or hepatitis B C infection. The diagnosis HCC relies heavily on diagnostic imaging, and high sensitivity specificity Liver Imaging Reporting Data System (LI-RADS) classifi...

Background Hepatocellular carcinoma (HCC) is a high-incidence and significant cause of cancer globally. HCC the world's third most common death-related sixth tumor. In HCC, various cellular signaling activated to ensure malignancy transformation, angiogenesis, metastasis. The efficient pathway in mitogen-activated protein kinase (MAPK), which controls regulates apoptosis. mutant k-ras gene led ...

Microwave ablation (MWA) is a promising minimally invasive therapy for hepatocellular carcinoma (HCC). However, the efficiency of MWA in treating HCC evidently limited by incomplete large...

As one of the most common malignancies worldwide, Hepatocellular carcinoma (HCC) has been treated by Sorafenib, which is first approved target drug FDA for advanced HCC. However, resistance obstacles to its application. a typical characteristic solid tumors, hypoxia become key cause chemotherapy and radiotherapy. It important elucidate underlying mechanisms Sorafenib under hypoxia. In this stud...

conclusions scc, lgdn, and hgdn are common associated findings and precursors of hcc in livers infected with hepatitis b. a strict follow-up and a precise and thorough sampling of livers with scc and any abnormal dysplastic nodules (dns), especially those larger than 1 cm, are highly recommended because these dns are highly associated with malignancy. results among all explanted cirrhotic liver...

the proliferation of hepatocellular carcinoma (hcc) cells is one of the leading causes of liver cancer mortality in humans. the inhibiting effects of matrine on hcc cell proliferation have been studied, but the mechanism of that inhibition has not been fully elucidated. since, apoptosis plays an important role in hcc cell proliferation. we examined the apoptosis-inducing effect of matrine on tu...