Stauffer syndrome is characterized by abnormal liver function tests, hepato-splenomegaly, histologic changes consistent with non-specific hepatitis, and recovery of these abnormalities after nephrectomy, in patients with RCC. Few cases have been described with paraneoplastic cholestatic jaundance of RCC in the literature. We report a case of a female patient presenting with advanced renal cell ...

Background: The economic cost of and liver and kidney diseases in Sub Saharan Africa remain prohibitive, hence the quest for medicinal foods that can reverse hepato-renal damages. The aim of this study is to investigate the hepato-renal protective effect of wild edible P.tuber-regium on carbon tetrachloride (CCl4) induced oxidative stress in male Sprague–Dawley rats. Method: Thirty six rats wer...

BACKGROUND/AIMS Natural honey has many biological activities including protective effect against toxic materials. The aim of this study was to evaluate the protective effect of carob honey against lead-induced hepato-renal toxicity and lead-induced anemia in rabbits. METHODS Twenty four male rabbits were allocated into four groups six rabbits each; group 1: control group, received distilled w...

Pharmacological and cytogenetic evaluations of the protective effects of polyethoxylated castor oil cremophor-EL (cremophor) against hepato, renal and bone marrow toxicity induced by gamma irradiation in normal rats were carried out. A single dose of irradiation (6 Gy) caused hepatic and renal damage manifested biochemically as an elevation in levels of serum alanine and aspartate aminotransfer...

Extracorporeal shock wave lithotripsy (ESWL) is a standard treatment method used for the treatment of renal calculi and upper ureteral calculi. Acute pancreatitis is a serious condition which develops due to multiple etiologic factors and is characterized by autodigestion of the pancreas. A case of acute pancreatitis which developed following ESWL performed for right renal calculi treatment is ...

Peroxisomes are subcellular organelles catalyzing a number of indispensable functions in cellular metabolism. The importance of peroxisomes is stressed by the existence of an expanding number of genetic diseases in which there is an impairment of one or more peroxisomal functions. The prototype of this group of diseases is the cerebro-hepato-renal syndrome of Zellweger (ZS), first described as ...

Background: Acetaminophen (Paracetamol; PCM), commonly utilized as analgesic and antipyretic drug in many painful and febrile disorders, has been found to induce liver and renal disorders in both animals and humans. Its administration in a high dose causes hepatic and renal toxicities and results in hepato-renal cell deaths by activating multiple stress pathways. Objective: This study aimed to ...