Background: We explored the effect of vitamin D receptor gene (VDR) polymorphisms in response to PEG-IFN treatment in Egyptian chronic hepatitis B (CHB) patients. Methods: Two hundred hepatitis B virus (HBV) patients (42.3±10.7 years) on PEG-IFN α-2a (180 μg /kg for 48 weeks) and one hundred control subjects (37.3 ±12 years) were enrolled in the study. Vitamin D levels a...

evidence for more than one etiologic agent has been recognized only since the 1940s, when 2 viruses [hepatitis A virus (HAV) and hepatitis B virus (HBV)] were thought to account for all disease. In the past 20 years, 3 additional hepatitis agents [hepatitis C virus (HCV), hepatitis D virus (HDV), and hepatitis E virus (HEV)] have been discovered, and there is evidence for at least one additiona...

Hepatitis B virus co-infection with C and/or D is known to result in a more deleterious disease than chronic HBV mono-infection, resulting faster progression cirrhosis and hepatocellular carcinoma. This study aimed at determining the serological prevalence of infections among carriers frequency e Antigen tertiary hospital South-East, Nigeria. cross-sectional involving 72 consenting participants...

INTRODUCTION Chronic hepatitis is a liver disease in the form of continuous inflammation and necrosis for at least 6 months. There are many causes of chronic hepatitis, including genetic disorders, drugs, toxins, autoimmune, idiopathic; but the most common cause is viral. The virus that causes chronic viral hepatitis is the hepatitis B virus (HBV), hepatitis C virus (HCV), as well as hepatitis ...

conclusions the main and frequent hbv genotype among azerbaijani patients with chronic hepatitis b virus infection was genotype d followed by genotype a. results the mean age of patients was 35.9 ± 11.7 years (19-66). of 103 patients, 72 (69.9%) were male. in the present study, the predominant hbv genotype was d (93.2%) followed by genotype a (5.8%) and concurrent infection with a and d genotyp...

introduction and aims: although a few studies have done in our country in the field of hepatitis d, its risk factors are not clearly known. this study was conducted with the aim of assessing the relative frequency and risk factors of hdv and the correlation between hdv and severity of liver damage. materials and methods: this was a cross sectional study. 280 hbsag positive subjects (including 1...

Background and Aims: Hepatitis D virus (HDV) can infect human population either as a superinfection or concurrent hepatitis B virus (HBV) infection. It is expected that presence of HDV infection is more prevalent in endemic HBV areas. Overall 5% of Iranian general populations are chronic HBV carriers. The aim of this study was to determine the seroprevalence of HDV and its clinical impact in ...