نتایج جستجو برای: hepatic cells

تعداد نتایج: 1461495  

Journal: :Journal of Materials Chemistry B 2021

In silico designed peptides showed high binding affinity towards activated human hepatic stellate cells, offering new strategies to target insulin-like growth factor 2 receptor in fibrotic liver and suggesting a potential for noninvasive diagnosis.

Obesity is a main reason of type 2 diabetes and also chronic exposure to arsenic (As)can produce diabetic symptoms. In previous studies, the association between high-fat dietand arsenic in the incidence of diabetes was found, but the role of beta cells activity, livermitochondrial oxidative stress, and hepatic enzymes (leptin, adiponectin and beta amylase)was unclear. Thus, present study was co...

Asadollah Mojtabaei,

Etiology of Physiologic Neonatal Hyperbili­rubinemia. Every newborn infant develop·s hyperbilirubinemia during the first week of life which is called "physiologic". There are several factors responsible for the development of physiologic hyperbilirubinemia, as follows:  1. Increased bilirubin production, due to a - Increased blood volume. b - Decreased R.B.C. survival time.  c - Increased in...

Journal: :acta medica iranica 0
ramin niknam gastroenterohepatology research center, shiraz university of medical sciences, shiraz, iran. and digestive disease research center, shariati hospital, tehran university of medical sciences, tehran, iran. razieh afrough digestive disease research center, shariati hospital, tehran university of medical sciences, tehran, iran. laleh mahmoudi department of pharmacotherapy, shiraz university of medical sciences, shiraz, iran.

although gastrointestinal bleeding is common, hemobilia due to the rupture of hepatic artery pseudoaneurysm is uncommon. we report a case of hemobilia which was successfully treated via angiography.

Journal: :Cell stem cell 2013
Orit Goldman Songyan Han Marion Sourisseau Noelle Dziedzic Wissam Hamou Barbara Corneo Sunita D'Souza Thomas Sato Darrell N Kotton Karl-Dimiter Bissig Tamara Kalir Adam Jacobs Todd Evans Matthew J Evans Valerie Gouon-Evans

Understanding the fetal hepatic niche is essential for optimizing the generation of functional hepatocyte-like cells (hepatic cells) from human embryonic stem cells (hESCs). Here, we show that KDR (VEGFR2/FLK-1), previously assumed to be mostly restricted to mesodermal lineages, marks a hESC-derived hepatic progenitor. hESC-derived endoderm cells do not express KDR but, when cultured in media s...

Journal: :Biochemical and Biophysical Research Communications 2007

Hossein Baharvand, Saeid Kazemi Ashtiani, Seyed Mahmoud Hashemi,

Background: Human embryonic stem cells (hESC), which are derived from the inner cell mass of the blastocysts, have been considered to be pluripotent cells. In this study we examine the differentiating potential of hESC into hepatocytes by characterization of the expression of endoderm and liver-specific genes. Methods: hESC were cultivated in suspension to form aggregates, the embryoid bodies. ...

Journal: :iranian journal of basic medical sciences 0
ghasem mosayebi molecular and medicine research center, school of medicine, arak university of medical sciences, arak, iran sayyed mohammad moazzeni department of immunology, school of medical sciences, tarbiat modarres university, tehran, iran

introduction dendritic cells (dcs) are bone marrow-derived cells, which migrate to lymphoid and non-lymphoid organs via blood. liver dcs are believed to play an important role in the regulation of hepatic allograft acceptance. however, because of inherent difficulties in isolating adequate numbers of dcs from liver, limited information is available on the phenotype and functions of liver dcs. t...

Journal: :Advanced Materials 2023

Drug Delivery In article number 2212206, Ying Zhao, Xiaolong Qi, Guangjun Nie, and co-workers propose a liver sinusoid capillarization hepatic stellate cells activation combined regulation strategy for fibrosis treatment. Liver fenestrae restoration enhances the transport efficiency of nanomedicine through wall, which represents promising approach

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