نتایج جستجو برای: hemoglobinuria
تعداد نتایج: 2365 فیلتر نتایج به سال:
The clinical hallmark of paroxysmal nocturnal hemoglobinuria (PNH) is episodic hemoglobinuria, and it was this feature that captured the attention of European physicians in the latter half of the 19th century, resulting in careful observational studies that established PNH as an entity distinct from paroxysmal cold hemoglobinuria and march hemoglobinuria. Curiosity about the etiology of the noc...
Myoglobin and hemoglobin are often present in the urine of hospitalized patients. Differentiating between the two is difficult but important, and textbooks still may contain misconceptions regarding these two proteins. Here we discuss(a)the difficulties of detection, (b) how to differentiate myoglobinuria from hemoglobinuria, (c) the importance of such differentiation, (d) the etiology of acute...
With babesiosis in dogs, the capillary network is especially strongly affected due to stimulation of hemostasis system and development thrombus formation microvasculature. Acute renal failure even death animals are caused by shock phenomena syndrome disseminated intravascular coagulation. Clinical, laboratory (hematological, biochemical, coagulometric, hemodynamic, enzyme immunoassay) methods r...
Objective: To discuss the implementation of technical advances in laboratory diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria for validation of high-sensitivity flow cytometry protocols. Methods: A retrospective study based on analysis of laboratory data from 745 patient samples submitted to flow cytometry for diagnosis and/or monitoring of paroxysmal nocturnal hemoglobinuria. ...
BACKGROUND Pregnancy in women with paroxysmal nocturnal hemoglobinuria is rare, with few reports on maternal and fetal mortality rates. DESIGN AND METHODS A specific questionnaire designed to solicit data on pregnancies in women with paroxysmal nocturnal hemoglobinuria was sent to all members of the French Society of Hematology in January 2008. RESULTS We identified 27 pregnancies in 22 wom...
Studies on 3 cases of march hemoglobinuria were recently reported from this laboratory and the existing literature concerning this syndrome was reviewed (1). In 1 patient of our series and in some other reported instances, frank hemoglobinuria has been observed following walks of only 20 minutes' duration. Such occurrences are obviously unusual and are considered to be due to some as yet unreco...
paroxysmal nocturnal hemoglobinuria (pnh) is a rare hematologic disorder that manifests with hemolytic anemia, thrombosis, and peripheral blood cytopenias.acute abdominal pain is one of the pnh clinical manifestations due to venous thrombosis of intra-abdominal sites including hepatic, portal, mesenteric, and splenic veins.eculizumaband allogeneic bone marrow transplantation (bmt) arethe only w...
BACKGROUND Thrombosis is the major risk factor for death in patients with paroxysmal nocturnal hemoglobinuria. Previous case reports indicate that venous thrombosis in patients with paroxysmal nocturnal hemoglobinuria is amenable to thrombolysis. DESIGN AND METHODS We reviewed the outcome of thrombolytic therapy for patients with paroxysmal nocturnal hemoglobinuria who had thromboses refracto...
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