to evaluate off-label and off-nccn guidelines uses of antineoplastic drugs in a major chinese hospital.totally 1122 patients were selected from july to december 2011. then, the off-label and off-nccn guidelines uses of antineoplastic drugs were analyzed.in 798 of 1122 patients (71.12%), drugs were used for off-label. in 317 of 1122 patients (28.25%), the drugs were prescribed for off-label and ...

Several factors have been associated with the presence of abnormally high plantar foot pressure including: (i) increased body weight, (ii) foot structure and (iii) walking strategy. It is predicted that the biomechanics of the foot is influenced by the structure of the foot, primarily the Medial Longitudinal Arch. The objective of this study was to examine if Body Mass Index and the foot arch h...

We compared the electromyographic (EMG) signals of lower extremity muscle groups in 10 children with hemiplegic cerebral palsy (CP) while walking barefoot and in a hinged ankle-foot orthosis (HAFO). All children had excessive plantarflexion and initial toe-contact on the affected side when walking barefoot, a typical gait pattern for hemiplegic patients. The patients walked with a physiological...

Assessment of gait deficits relies on accurate segmentation based the key events heel strike (HS) and toe-off (TO). Kinematics-based estimation has shown promise in this regard, especially using leg velocity signal gyroscopic sensors. However, its validation for amputee population is not established literature. The goal study to assess accuracy lower-leg angular determining TO HS instants popul...

The determination of gait events such as heel strike and toe-off provide the basis for defining stance and swing phases of gait cycles. Two algorithms for determining event times for treadmill and overground walking based solely on kinematic data are presented. Kinematic data from treadmill walking trials lasting 20-45s were collected from three subject populations (healthy young, n=7; multiple...

The duration of stance and swing phase and step and stride length are important parameters in human gait. In this technical note a low-cost ultrasonic motion analysis system is described that is capable of measuring these temporal and spatial parameters while subjects walk on the floor. By using the propagation delay of sound when transmitted in air, this system is able to record the position o...

Nowadays, a growing number of young and more active patients receive hip replacement. More strenuous activities in such patients involve higher friction and wear rates, with friction on the bearing surface being crucial to ensure arthroplasty survival in the long term. Over the last years, the polycarbonate-urethane has offered a feasible alternative to conventional bearings. A finite element m...

wide variety of timings and techniques has been used based on the housing, production, availability of requirements etc. this current study was done for a morphologic evaluation of the cow's digit in different trimming times. a dairy herd with 2200 milking cow, free stalls barns, average daily production of 36 liters per cow was selected. forty cows were assigned to four groups based on hoof tr...

Biotechnology is playing an extremely important part in medical advances. In actuality, they are the basis of pathology diagnosis, which provides doctors with quantitative data required to choose best treatment. This study looks at facts a case weak muscular activity and devises solutions help disabled or very ill for specialist improve patient's condition by choosing accurate would enhance the...