Heavy metal poisoning is a serious threat in the world of industrialization as almost all the industries use heavy metals in one or the other way. These heavy metals do harm to vitals such as liver, kidney, lung and blood. Liver is the site of biotransformation of xenobiotic substances. Liver is thus the most affected affected organs of the body. The present study highlights toxic stress of mer...

A 21-year-old gentleman, a worker in a mobile phone shop, was admitted with rhabdomyolysis, renal failure, and pulmonary edema requiring mechanical ventilation and hemodialysis. After extensive workup and ruling out other causes, heavy metal poisoning was considered. Investigations during the course of the hospital stay revealed chromium poisoning. With repeated hemodialysis, his parameters nor...

Lead is a dangerous heavy metal which is widely spread in the environment. Lead content in the air, food and tap water has increased several folds during recent years due to extensive use of this metal in petrol, paints, battery and other industries (Tuormaa, 1995). Despite of attempts for reducing the exposure to this metal, there are still some reports of cases with severe lead toxicity (Hers...

Heavy metals are, unfortunately, present in the air, water, and food supply. Cases of severe acute lead, mercury, arsenic, and cadmium poisoning are rare; however, when they do occur an effective, non-toxic treatment is essential. In addition, chronic, low-level exposure to lead in the soil and in residues of lead-based paint, to mercury in the atmosphere, in dental amalgams and in seafood, and...

Exposure to heavy metals is a common phenomenon due to their environmental pervasiveness. Metal intoxication particularly neurotoxicity, genotoxicity, or carcinogenicity is widely known. This review summarizes our current understanding about the mechanism by which metalloids or heavy metals (particularly arsenic, lead, cadmium and mercury) induce their toxic effects. The unifying factor in dete...

Of the known elements, nearly 80% are either metals or metalloids. The highly reactive nature of most metals result in their forming complexes with other compounds such oxygen, sulfide and chloride. Although this reactivity is the primary means by which they are toxic, many metals, in trace amounts, are vital to normal physiological processes; examples include iron in oxygen transport, manganes...

Interest in ethylenediaminetetraacetic acid (EDTA) arises from its ability to combine with metal ions to form water-soluble chelates. Several important biological applications have been made of this property. The material has been shown to be effective (a) in mobilizing radioactive elements such as Pu, Am, and Y from the skeleton (1, 2), (b) as a valuable therapeutic agent in the treatment of p...