Introduction: Boron neutron capture therapy (BNCT) is recommended to treat the glioblastoma tumor. It is well known that neuron beams are more effective treatment than photon beams to treat hypoxia tumors due to interaction of neutron with nucleus and production of heavy particles such as 7Li and alpha particle. In this study to evaluate the suitability of BNCT for treating of ...

Elevated sympathetic tone and b-AR desensitization are characteristics associated with heart failure (HF) contributors to the initiation of arrhythmia. Studies have shown that altered responsiveness in HF leads compartmentalization imparied sub-cellular cAMP signaling. Yet, if signaling is heterogeneously remodeled throughout intact heart, how this may contribute arrhythmia unknown. To assess w...

PURPOSE To investigate respiration-induced heart motion for left-sided breast irradiation using a four-dimensional computed tomography (4DCT) technique and to determine novel indications to assess heart motion and identify breast patients who may benefit from a gated treatment. METHODS AND MATERIALS Images of 4DCT acquired during free breathing for 20 left-sided breast cancer patients, who un...

INTRODUCTION Recent research showed radiation for breast cancer can increase heart risks (1, 2). In Ref. (2), it has been noted that for every Gy of radiation a women’s heart risk rises 7.4%. However, the correlation between radiation dose and heart tissue damage is still an open problem. A more accurate model of heart damage will significantly improve the heart safety for patients underwent ra...

PURPOSE To evaluate the relationship between the primary breast volume and dose received by the ipsilateral lung, heart (for left-breast cancers), and contralateral breast during primary breast irradiation using intensity-modulated radiation therapy (IMRT). METHODS AND MATERIALS Sixty-five patients with breast carcinoma were treated using 6-MV photons with IMRT technique using the Eclipse Pla...

BACKGROUND Carvedilol therapy reduces mortality in patients with chronic heart failure. Multi-centre studies suggest a low first dose failure rate and high levels of tolerability to carvedilol. Little is known, however, concerning the eligibility and tolerance to treatment with carvedilol within a district general hospital setting. AIM To evaluate the eligibility and tolerance of patients wit...