Abstract Introduction Cardiac function has been found to decrease within the first 24 hours after burn injury and documented stay depressed for up 72 hours. Cardioprotective drugs such as sildenafil, PJ34, MitoTEMPO, ZLN005 have shown counteract this dysfunction when administered 1 hour before injury. However, there remains limited knowledge on effects of cardioprotective in early phase Methods...

abstract background: many people suffer from burn injuries every year, and burns make the patients undergo surgeries and years of rehabilitation. burns lead to more years of disability, compared to cancer or heart diseases. epidemiologic studies are needed to reveal the span, impact, and related factors of burns to help take appropriate efforts to reduce its mortality and morbidity. materials a...

It is difficult to define all cardiac risk factors in the course of burn treatment. The adequate function of the circulatory system is the main factor in successful therapy. The aim of this study was to define, using a transoesophageal Doppler system, the cardiac circulatory risk factors of death in burn patients. One hundred and forty-seven burn patients were divided into two groups defined as...

burns are injuries which may require long hospitalization and may result in important impairment and disability. burn injuries are still common especially in developing countries. assessment of the epidemiology of burns is very important for introduction of preventive methods. this study was conducted in yazd to assess and describe the epidemiology of burns including its main causes, and its de...

Deceptive Nature of Atrial Premature Contractions: Ablating 2 Arrhythmias With 1 Burn Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2014 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.114.011155 2014;130:e148-e150 Circulation. http://circ.ahajournal...

Background: Pain management of children with a burn is one of the most important issues in pediatrics medicine. Non-pharmacological methods of pain control can play an important role in suitable some patients. This study was aimed conducted with the aim ofto investigating investigate the effect of Medical-directed play on the severity of pediatric pain during burn dressing change in children. ...

BACKGROUND Burn injury results in a chronic inflammatory, hypermetabolic, and hypercatabolic state persisting long after initial injury and wound healing. Burn survivors experience a profound and prolonged loss of lean body mass, fat mass, and bone mineral density, associated with significant morbidity and reduced quality of life. Understanding the mechanisms responsible is essential for develo...

Objective. Lipid peroxidation plays a critical role in burn-induced plasma leakage, and ulinastatin has been reported to reduce lipid peroxidation in various models. This study aims to examine whether ulinastatin reduces fluid requirements through inhibition of lipid peroxidation in a swine burn model. Methods. Forty miniature swine were subjected to 40% TBSA burns and were randomly allocated t...

The purpose of the present study was to determine whether burn injury decreases myocardial protein synthesis and potential contributing mechanisms for this impairment. To address this aim, thermal injury was produced by a 40% total body surface area full-thickness scald burn in anesthetized rats, and the animals were studied 24 h late. Burn decreased the in vivo-determined rate of myocardial pr...

Recent studies from our laboratory have shown that alcohol and burn injury impair intestinal barrier and immune functions. Although multiple factors can contribute to impaired intestinal barrier function, such an alteration could result from a decrease in intestinal blood flow (BF) and oxygen delivery (DO2). Therefore, in this study, we tested the hypothesis that alcohol ingestion before burn i...