Background.  Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) coinfection has emerged as an important cause of morbidity and mortality. We determined the response to Truvada-based first-line combination antiretroviral therapy (cART) in HIV/HBV-coinfected verus HIV-monoinfected patients in Botswana. Methods.  Hepatitis B virus surface antigen (HBsAg), HBV e antigen (HBeAg), and HBV...

We retrospectively reviewed 413 recipients with hematologic malignancies who underwent hematopoietic stem cell transplantation (HSCT) between June 1986 and March 2013. Recipients with antibody to hepatitis B core antigen (anti-HBc) and/or to hepatitis B surface antigen (anti-HBs) were regarded as experiencing previous hepatitis B virus (HBV) infection. Clinical data of these recipients were rev...

  Background and Objective: Presence of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is defined, as isolated anti-HBc. little is known about the clinical significance of the isolated anti-HBc in hepatitis B virus (HBV) infections. The aim of this study was to assess the significance of anti-HBc as the onl...

Objective: To study the clinical value of hepatitis B virus pregenomic RNA (HBV-pgRNA) detection in treatment B. Methods: 60 patients with were included study. Serum HBV-pgRNA and HBV DNA levels different phases infection during detected, serum surface antigen (HbsAg) titer was detected by chemiluminescent immunoassay. extracted from liver biopsy tissue, covalently closed circular to predict th...

BACKGROUND The overall prevalence of hepatitis B virus (HBV) infection in China is declining. The purpose of this study was to use a community-based epidemiological study to update the infection status of hepatitis B virus (HBV) in mountainous regions of China, and to evaluate the impact of the Expanded Program of Immunization (EPI) on HBV transmission. METHODS In total, 10,383 participants w...

Serum hepatitis B virus (HBV) markers are the most important data for epidemiological screening and clinical diagnosis of HBV infection, especially in endemic areas. We compared the results of the Roche Modular Analytics E170 assay, the Abbott Architect i2000 assay, and an immunoradiometric assay (IRMA) for HBV surface antigen (HBsAg), anti-HBV surface antigen (anti-HBs), HBV e antigen (HBeAg),...

We have identified long-incubation viral agents that share epitopes with hepatitis B virus (HBV). During chimpanzee infectivity studies, these agents may be recognized in the liver since they possess complementary nucleic acid sequences with HBV DNA; the genomic size was found to be 3.2 kilobases, identical to that of HBV. Liver injury was produced and there was antigen expression in hepatocyte...

introduction: occurrence of detectable amounts of viral antigen or viral particles in the blood of infected patients with hepatitis b virus (hbv) is a significant characteristic of hbv infection. detection of hbv antigen or its dna among individuals of a community is a crucial factor to know the burden of hbv infection. hepatitis b surface antigen (hbsag) is a suitable marker of hbv infection b...

Role of MHC class I HLA A2 HC and trimeric molecules on the binding of exogenous HBV core antigen was studied in Hela cells transfected with MHC class 1 HLA A2. HC and trimeric HLA A2 molecules could be identified with specific monoclonal antibodies. HC and trimeric HLA-A2 molecules exist in varying proportion on the cell surface of Hela cells. MHC class I HC molecules on the cell surface do no...

Hepatitis B virus (HBV) reactivation in patients with resolved HBV infection was found in 23 (4%) of 552 newly hepatitis B surface antigen-positive patients in Japan. Because one-fourth of cases develop into fulminant hepatic failure and mortality is 100%, management of HBV reactivation in patients with resolved HBV infection should be discussed.