Zusammenfassung Wissen ist in der modernen Sozialpädagogik besonderem Maße mit Ungewissheiten konfrontiert, die jenseits bloßer Informationen liegen. In diesem den Themenschwerpunkt einleitenden Beitrag werden Herausforderungen auch am Beispiel Pandemie veranschaulicht um dafür zu plädieren, dass eine steigende Komplexität nicht dazu führen muss und darf, als ausschließlich relativ willkürlich ...

The maize transposon Activator (Ac) was the first mobile DNA element to be discovered. Since then, other elements were found that share similarity to Ac, suggesting that it belongs to a transposon superfamily named hAT after hobo from Drosophila, Ac from maize, and Tam3 from snapdragon. We addressed the structure and evolution of hAT elements by developing new tools for transposon mining and se...

In the framework of generalized Lorenz-Mie theory, laser beams are described by sets of beam-shape coefficients. The modified localized approximation to evaluate these coefficients for a focused Gaussian beam is presented. A new description of Gaussian beams, called standard beams, is introduced. A comparison is made between the values of the beam-shape coefficients in the framework of the loca...

The small subunit (SSU) processome is a ribosome biogenesis intermediate that assembles from its subcomplexes onto the pre-18S rRNA with yet unknown order and structure. Here, we investigate the architecture of the UtpB subcomplex of the SSU processome, focusing on the interaction between the half-a-tetratricopeptide repeat (HAT) domain of Utp6 and a specific peptide in Utp21. We present a comp...

The histone acetyl transferases CREB-binding protein (CBP) and its paralog p300 play a critical role in numerous cellular processes. Dysregulation of their catalytic activity is associated with several human diseases. Previous work has elucidated the regulatory mechanisms of p300 acetyltransferase activity, but it is not known whether CBP activity is controlled similarly. Here, we present the c...

Deutschland steht 2009 vor einem überaus schwierigen Jahr. Vorausschauende Manager schielen aber weniger auf die nicht beeinflussbaren Eckdaten, sondern finden heraus, welche Verbesserungspotenziale in ihrer Firma schlummern. Eine Alternative zu Cost-Cutting-Programmen kann die Optimierung des Projektmanagements sein. Ein kritischer Blick auf den Markt der dafür erforderlichen Projektmanagement...

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It is shown that the photon position operator $\hat{\vec{X}}$ with commuting components can be written in momentum representation as $\hat{\vec{X}}=i \hat{\vec{D}}$, where $\hat{\vec{D}}$ a flat connection tangent bundle $T(\mathbb{R}^3 \setminus \{ (0,0,k_3) \in \mathbb{R}^3 : k_3 \geq 0\})$ over $\mathbb{R}^3 0\}$ equipped Cartesian structure. Moreover, such $2$-planes orthogonal to are paral...