Almost all (if not all) models are burdened with uncertainty. Even if we set aside the difficulties in choosing the adequate level and complexity of a mathematical model, the problem of uncertainty in the numerical values of input parameters is omnipresent. In civil or mechanical engineering, for instance, the knowledge of material parameters is essential. Their numerical values can be found in...

Clinical practice guidelines (CPGs) contain evidence-based recommendations to guide clinical care, policy development, and quality of care improvement. A recent systematic review of epilepsy guidelines identified considerable variability in the quality of available guidelines. Although excellent frameworks for CPG development exist, processes are not followed uniformly internationally, and reso...

Reading this handbook of " Cardiothoracic " surgery, I am reminded of the Peter Cook & Dudley Moore sketch about the one legged man auditioning for the role of Tarzan: " I love your right leg … I have nothing against your right leg … unfortunately neither do you! " Well, I have nothing against the cardiac surgery side of this book, it is excellent. Unfortunately the Thoracic component is almost...

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BACKGROUND The purpose and contribution of supplementary search methods in systematic reviews is increasingly acknowledged. Numerous studies have demonstrated their potential in identifying studies or study data that would have been missed by bibliographic database searching alone. What is less certain is how supplementary search methods actually work, how they are applied, and the consequent a...

Objective: Various types of handbooks that summarize and record health information (health handbooks) have been used in Japan for many years. The purpose this study was to explore ways evaluate the understandability usability commonly printed Japan. Methods: An internet search performed identify were then collected, searched, evaluated quality functionality health-information. overall assessed ...

in different projects the speed of different machinery can be estimated using manufacturer's handbooks and a number of modification factors to consider the environmental effects, type of the project and status of site management. since the statuses of different factors of the domestic projects are totally different from those of the international projects, there is a wide discrepancy betwe...