The object management architecture (OMA) has been recognized as a de facto standard in the development of object services in a distributed computing environment. In a distributed system, the provision for failure-recovery is always a vital design issue. However, the fault-tolerant service has not been extensively considered in the current OMA framework, despite the fact that an increasing numbe...

Perivascular epithelioid cell tumor (PEC-oma) is a rare mesenchymal neoplasm. Literature reports more than 100 cases of PEC-oma, a third of which is of uterine or uterine retroperitoneum origin. The case of a 59-year-old woman presented here is, to the best of our knowledge, the first described fast uterine PEC-oma recurrence of the tumor of the gastrointestinal tract origin. In this text the a...

BACKGROUND ACE inhibitors (ACEIs) improve insulin resistance and prevent type 2 diabetes, possibly mediated by inhibition of bradykinin (BK) degradation. The vasopeptidase inhibitor omapatrilat (OMA) raises BK to a greater extent than ACEIs by dual enzyme inhibition, whereas its insulin-sensitizing effects and mechanisms have not been investigated. METHODS AND RESULTS We compared the insulin-...

As mobile devices and functionalities have increased and become intelligent, many related problems have occurred. Especially, the degraded quality of service caused by the shadow area has given the end-users much inconvenience. In addition, the credibility of the service providers, the network operators, and the manufacturers of the mobile devices have also decreased. In order to solve these pr...

In vertebrates, oocytes undergo maturation, arrest in metaphase II, and can then be fertilized by sperm. Fertilization initiates molecular events that lead to the activation of early embryonic development. In Caenorhabditis elegans, where no delay between oocyte maturation and fertilization is apparent, oocyte maturation and fertilization must be tightly coordinated. It is not clear what coordi...

Smart ob jects are devices with computational and communication capabilities connected to the Internet forming the so called Internet of Things (IoT). The IoT enables many applications, for instance outdoor lighting con­ trol, smart energy and water management, or environmental sensing in a smart city environment. Security in such scenarios remains an open challenge due to the resource-constrai...

Omalizumab (OMA), a humanized anti-immunoglobulin E (IgE) monoclonal antibody was approved in the EU in 2005 as an add-on therapy for patients with severe persistent allergic asthma (AA). We present an overview of recent developments in the use of OMA for this indication. Approval for pediatric use: followed the completion of two clinical trials in children 6 to <12 years of age with moderate-t...

In C. elegans, four asymmetric divisions, beginning with the zygote (P0), generate transcriptionally repressed germline blastomeres (P1-P4) and somatic sisters that become transcriptionally active. The protein PIE-1 represses transcription in the later germline blastomeres but not in the earlier germline blastomeres P0 and P1. We show here that OMA-1 and OMA-2, previously shown to regulate oocy...

Mild heart failure is characterized by increases in atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in the absence of activation of the renin-angiotensin-aldosterone system (RAAS). Vasopeptidase (VP) inhibitors are novel molecules that coinhibit neutral endopeptidase 24.11, which degrades the natriuretic peptides (NPs) and ACE. In a well-characterized canine model of mild h...

Organized mesoporous aluminas (OMA) are materials that present interesting properties as catalytic supports in reactions in which bulky molecules are involved. In this work, a number of OMA were prepared using a non-ionic structure directing agent (a tri-block co-polymer). The study of the quantitative influence of some OMA synthesis conditions (water aluminium ratio (H2O:Al), ageing temperatur...