Cones release glutamate-filled vesicles continuously in darkness, and changing illumination modulates this release. Because sustained release in darkness is governed by vesicle replenishment rates, we analyzed how cone membrane potential regulates replenishment. Synaptic release from cones was measured by recording postsynaptic currents in Ambystoma tigrinum horizontal or OFF bipolar cells evok...

Rajasthan's Bikaner District, part of the Thar Desert, is experiencing problems with falling groundwater levels, high salinity, fluoride and nitrate concentrations. Therefore, quality studies are underway to determine suitability for drinking purposes in district. Quality analysis performed using parameters such as Conductivity (EC), Total Dissolved Solids (TDS), pH, Calcium, Potassium, Sodium,...

This paper presents an inventory model for deteriorating items over a ®nite time horizon where the demand increases linearly with time. The method is developed by assuming that the successive replenishment cycle lengths are the same. Many O.R. scientists/researchers obtained an optimal replenishment schedule where the replenishment cost is constant in each cycle length over the ®nite time horiz...

This paper examines several inventory replenishment policies for a make-to-order inventory–production system that consists of a production workshop and a warehouse. Demands arrive to the production workshop according to a Poisson process, and are processed in an FCFS manner. The production workshop requires that the warehouse provides, as needed, raw materials for use in the production process....

生态补水是维持和改善白洋淀生态环境的重要途径.为研究生态补水对白洋淀水环境的影响，分别在补水前与补水后采集淀水、河水及地下水样品，分析区域地表水和地下水水化学特征.结果表明：（1）白洋淀补水前、后地表水与地下水的水化学组成中Na+为主要阳离子，补水后阴离子以HCO3-为主，淀区南部地表水电导率高；补水后地表水与地下水Ca2+、Mg2+和HCO3-浓度显著增加，水体电导率降低.（2）补水前地下水为Na-HCO3型水，地表水主要为Na-Cl·SO4及Na-Cl·HCO3类型；补水后地表水与浅层地下水向Ca·Mg-HCO3型演化，深层地下水水化学类型基...

This paper deals with an optimal replenishment policy for deteriorating items with multi-variate demand and partial backlogging. The proposed model allows for (1) multivariate demand replenishment cycles, (2) partial backlogging, and (3) time-varying shortage intervals. Consequently, the proposed model is in a general framework for that inventory models includes these above assumptions. We show...

Under basal conditions the action potential firing rate of adrenal chromaffin cells is lower than 0.5 Hz. The maintenance of the secretory response at such frequencies requires a continuous replenishment of releasable vesicles. However, the mechanism that allows such vesicle replenishment remains unclear. Here, using membrane capacitance measurements on mouse chromaffin cells, we studied the me...

The contributions from terrestrial water sources to sea-level rise, other than ice caps and glaciers, are highly uncertain and heavily debated1–5. Recent assessments indicate that groundwater depletion (GWD) may become the most important positive terrestrial contribution6–10 over thenext 50years, probably equal in magnitude to the current contributions from glaciers and ice caps6. However, the ...