easily degradating and various isomeric forms of rapamycin (sirolimus) face the determination of this compound to many challenges. in this study, we developed and validated the isocratic reversed phase high performance liquid chromatographic (rp-hplc) method for rapamycin. separation was performed on a c8 column (mz, 15 × 4.6 mm, 5 µm particle size) using methanol:water (80:20 v/v) as the mobil...

background: to investigate the expression of tnf-α, il-6, il-10 in the plasma of patients with lung cancer who received radiation therapy (rt), and to analyze the correlation between these cytokines and radiation pneumonitis (rp). materials and methods: patients with lung cancer who received 3d-crt in our hospital were prospectively evaluated. circulating cytokine levels were measured with elis...

the development of a number of different rapid prototyping (rp) technologies with wide-ranging capabilities, features and applications has created the problem of selecting an appropriate rp system for engineering educational institutions as well as manufacturing organizations intending to adopt this new technology. this paper presents an rp decision support system (rp dss) for ranking and selec...

background: methionine has been suggested as the firstlimitingamino acid for milk production in ruminants. it is importanthow to increase milk protein yield and milk fat in dairy ruminants.objectives: this study was set to investigate the effect of rumenprotected methionine (rpmet) on milk composition of lactatingcashmere rayeni goats. methods: 40 healthy singletoncashmere rayeni goats about 3 ...

for vectors x, y ∈ rn, it is said that x is left matrix majorizedby y if for some row stochastic matrix r; x = ry. the relationx ∼` y, is defined as follows: x ∼` y if and only if x is leftmatrix majorized by y and y is left matrix majorized by x. alinear operator t : rp → rn is said to be a linear preserver ofa given relation ≺ if x ≺ y on rp implies that t x ≺ ty onrn. the linear preservers o...

a method for determination of juglone in leaves and hulls of pterocarya fraxinifolia was developed, based on rp-hplc. this compound was extracted from leaves and hulls by chloroform refluxing about 2 hours. the chloroform was evaporated under low pressure at   50 ºc to produce a dry residue. the remained materials were dissolved in acetonitrile to be used for determination of this compound. app...

OBJECTIVES Discordance between the Gleason score (GS) on needle biopsy (NB) and the GS of the radical prostatectomy (RP) specimen is a common finding. The objective of this study was to evaluate the prognostic significance of these discrepancies with respect to outcomes following RP. METHODS In the study, 6625 men treated by RP were categorized as having NB=RP (68.8%), NBRP ...