The title 1:1 co-crystal, C11H14O3·C6H6N2O [systematic name: butyl 4-hy-droxy-benzoate-isonicotinamide (1/1)], crystallizes with one mol-ecule of butyl-paraben (BPN) and one mol-ecule of isonicotinamide (ISN) in the asymmetric unit. In the crystal, BPN and ISN mol-ecules form hydrogen-bonded (O-H⋯N and N-H⋯O) dimers of paired BPN and ISN mol-ecules. These dimers are further connected to each ot...

An airborne gravimeter is one of the most important tools for gravity data collection over large areas with mGal accuracy and a spatial resolution of several kilometers. In August 2012, a flight test was carried out to determine the feasibility and to assess the accuracy of the new Chinese SGA-WZ strapdown airborne gravimeter in Greenland, in an area with good gravity coverage from earlier mari...

The 8th ICN: The largest item looming on the agenda for the ISN is our upcoming Congress in Vancouver (July 22-27). I can tell you that we are in excellent hands with Barb Beltz chairing the Congress Committee and Cathy Rankin as the Chair of the local organizing committee. Ron Harris-Warrick and Sten Grillner are the Congress Vice-Chairs. These folks, with excellent advice from the membership ...

Inclusive Social Network Services (ISN) represent an opportunity for ordinary people to access information and knowledge through the Web. Such systems should provide access for all, creating situations where users' diversity is respected and the access difficulties are minimized. The use of search mechanisms has been the main way to find information in the Web. However, such mechanisms are stil...

Salivary secretion results from reflex stimulation of autonomic neurons via afferent sensory information relayed to neurons in the rostral nucleus of the solitary tract (rNST), which synapse with autonomic neurons of the salivatory nuclei. We investigated the synaptic properties of the afferent sensory connection to neurons in the inferior salivatory nucleus (ISN) controlling the parotid and vo...

Cortical functions arise from excitatory recurrent connections and strong interactions between the principal excitatory and local inhibitory interneurons. What is the dynamic behavior of these networks and in what regime do they operate? Experiments in the hippocampus (Tsodyks et al, 1997) as well as the visual cortex (Ozeki et al, 2009) point to an inhibition stabilized regime of the E-I netwo...

Two mouse spleen cell-myeloma cell hybridomas (isn-1 and isn-3) which secrete IgGl molecules capable of precipitating prostaglandin I2 (PGIZ) synthase activity were selected and cloned. Immunoglobulins secreted by isn-1 and isn-3, but not by control hybridoma lines, caused the immunoprecipitation of the same, single ‘2sI-labeled protein (Mr = 52,000) from a mixture of 12SI-labeled proteins from...

The neural receptor tyrosine phosphatases DPTP69D, DPTP99A and DLAR are involved in motor axon guidance in the Drosophila embryo. Here we analyze the requirements for these three phosphatases in growth cone guidance decisions along the ISN and SNb motor pathways. Any one of the three suffices for the progression of ISN pioneer growth cones beyond their first intermediate target in the dorsal mu...