نتایج جستجو برای: granulocyte colonystimulating factor

تعداد نتایج: 851326  

2003
Kohsuke Yanagisawa Takahiko Horiuchi Shigeru Fujita

A new human leukemia cell line, designated as ME-1, was established from the peripheral blood leukemia cells of a patient with acute myelomonocytic leukemia with eosinophilia (M,E,). This cell line has the characteristic chromosome abnormality of M,E,, inv(l6) (p13q22). When cultured in RPMI 1640 medium containing 10% fetal calf serum, ME-1 cells were monoblastoid, but with the addition of cyto...

2006
Atsunobu Hiraoka Tadashi Ohkubo Minoru Fukuda

Fifty-five hematopoietic cell lines, including 19 T-, 16 B-, S pre-B-, 5 non-T non-B-, 1 erythroid, and 9 myeloid-monocytoidcells, were screened for production of human hematopoietic survival and stem cell growth factor (SCGF) by enzyme immunoassay using anti-SCGF monoclonal antibody. The KPB-M15 myeloid cell line constitutionally secreted a considerable quantity of SCGF, while other Tor myeloi...

2006
Yangxin Fu Gordon Watson JoaquÃ-nJ. Jimenez Yang Wang Diana M. Lopez

Using an immunogenic nonmetastatic murine mammary adenocarcinoma (Dl-DMBA-3) induced in BALB/c mice by dimethylbenzanthracene, we have previously shown that splenocytes from tumor bearers have depressed lymphocyte responses to mitogens and antigens, including tumor-associated antigens. In addition, they display decreased natural killer and T-cell cytotoxic activities. Macrophages from tumor-bea...

2010
Astrid Bergmann Claudia Eulenberg Maren Wellner Susanne Rolle Friedrich Luft Ralph Kettritz

Mineralocorticoid receptor (MR) activation by aldosterone controls salt homeostasis and inflammation in several tissues and cell types. Whether or not a functional MR exists in polymorphonuclear neutrophils is unknown. We investigated the hypothesis that aldosterone modulates inflammatory neutrophil responses via the MR. By flow cytometry, Western blot analysis, and microscopy, we found that ne...

Journal: :basic and clinical neuroscience 0
mohsen marzban mehrdad bakhtiary mehdi mehdizadeh mohamad taghi joghataei samideh khoei vahid pirhajati mahabadi

introduction: this study was designed to investigate the effects of granulocyte colony-stimulating factor (g-csf) administration in rats for 6 weeks after traumatic brain injury (tbi). methods: adult male wistar rats (n = 30) were injured with controlled cortical impact device and divided into four groups. the treatment groups (n = 10 each) were injected subcutaneously with recombinant human g-...

Journal: :international journal of reproductive biomedicine 0
behnaz sheikholslami mojdeh salehnia mojtaba rezazadeh

the cytokine of granulocyte macrophage colony stimulating factor (gm-csf) is a glycoprotein, which is synthesized in the female reproductive tract and has embryonic trophic effect in mammals. the objective of this study was to examine the optimal dosage of gm-csf to improve the mouse embryo development in vitro. to collect two and eight cells embryos, the pregnant nmri mice were sacrificed by c...

2016
Haowei He

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2016;5(S1) tau.amegroups.com Objective: The goal of this article was to investigate the diagnosis, treatment and mechanisms of the leukemoid reaction (LKR) associated with transitional cell carcinoma. Methods: A 64-year-old male patient presented with anuria. Color ultrasound imaging revealed a large bladder tumor. ...

2002
Jeff Canfield Steve Braun Chuxia Deng Hal E. Broxmeyer

Steel factor ELF) is a hematopoietic cytokine that synergizes with other growth factors to induce a greatly enhanced proliferative state of hematopoietic progenitor cells and factor-dependent cell lines. Even though the in vivo importance of SLF in the maintenance and responsiveness of stem and progenitor cells is well documented, the molecular mechanisms involved in its synergistic effects are...

Journal: :international journal of reproductive biomedicine 0
marcelo borges cavalcante fabrício da silva costa ricardo barini edward araujo júnior

background: recently, the use of granulocyte colony-stimulating factor (g-csf) has been proposed to improve pregnancy outcomes in reproductive medicine. objective: a systematic review of the current use of g-csf in patients who have difficulty conceiving and maintaining pregnancy was performed. materials and methods: two electronic databases (pubmed/ medline and scopus) were searched. study sel...

Journal: :iranian biomedical journal 0
لعیا قهاری laya ghahari منوچهر صفری manouchehr safari محمدتقی جغتایی mohamad taghi joghataei مهدی مهدی زاده mehdi mehdizadeh منصوره سلیمانی mansoureh soleimani

background: stroke is the third leading cause of death. hypothermia has been recognized as an effective method in reducing brain injury. in this study, we assessed the effects of granulocyte colony-stimulating factor (g-csf) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in wistar rats. methods: forty male rats were used in fiv...

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  • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->