Experiments on granule transport and the mean residence time in a rotary horizontal drum with inclined flights showed that the granules can be transported steadily. A model for granule transport based on the analysis of granule motion and other studies on inclined drums was developed to calculate the mean residence time of the granules, and verification experiments under different conditions we...

We investigated the ultrastructural characteristics and the granule major basic protein (MBP) content of hypodense eosinophils from patients with the hypereosinophilic syndrome who had at least 90% hypodense eosinophils in their peripheral blood and compared these cells to normodense eosinophils from normal persons. The hypodense cells (density less than 1.082) contained significantly less MBP ...

UO2/BeO interfacial thermal resistance (ITR) is calculated by diffuse mismatch model (DMM) and the effects of ITR on UO2-BeO conductivity are investigated. predicted DMM order 10-9 m2K/W. Using this ITR, conductivities theoretical models compared with experimental data. The results indicate that prediction applicable to interface between UO2 dispersed BeO, while not continuous BeO. If containin...

In this study, the feasibility of spatial filter velocimetry (SFV) as process analytical technology tool for the in-line monitoring of the particle size distribution during top spray fluidized bed granulation was examined. The influence of several process (inlet air temperature during spraying and drying) and formulation variables (HPMC and Tween 20 concentration) upon the particle size distrib...

Killing of virally infected cells or tumor cells by cytotoxic T lymphocytes requires targeting of lytic granules to the junction between the CTL and its target. We used whole-cell patch clamp to measure the cell capacitance at fixed intracellular [Ca2+] to study fusion of lytic granules in human CTLs. Expression of a fluorescently labeled human granzyme B construct allowed identification of lyt...