It is well established that organophosphate pesticides, such as diazinon, pose environmental and health risks. Diazinon is prone to rapid acidic hydrolysis, forming the less toxic compound 2-isopropyl-6-methyl-4-pyrimidinol (IMP). In this study, diazinon surface catalyzed hydrolysis was achieved by its adsorption to a composite, based on protonated poly (4-vinyl-pyridine-co-styrene) (HPVPcoS) a...

BACKGROUND Since organophosphorus pesticides are widely used for industry and insect control in agricultural crops, their fate in the environment is very important. Pesticide contamination of surface water has been recognized as a major contaminant in world because of their potential toxicity towards human and animals. The objective of this research was to investigate the influence of various p...

Diazinon has been used extensively in the past as part of California eradication programs for tephritid fruit flies (Diptera: Tephritidae) as a soil drench, but it is being phased out for this purpose in the United States. Therefore, in this study, the toxicity of Platinum, Force, Admire, Regent, and Warrior was estimated after application to sand and soil as drenches for control of the Mediter...

Diazinon is an organophosphorus insecticide (OPP) that is used as a pesticide for Chilo suppressalis (WLK) (Lep., Pyralidae) in rice fields. The extraction of diazinon from soil and the stems of rice plants has been carried out by microwave-assisted extraction (MAE) and the results compared with ultrasonic extraction (USE). The best parameters for MAE are hexane-acetone (8:2 v/v) as a solvent, ...

Four diazinon-degrading bacteria were isolated from agricultural soil by using an enrichment technique. The biochemical analysis and molecular method including RFLP indicated that these isolates were identical, and one strain designated DI101 was selected for further study. Phylogenetic analysis based on 16S rDNA sequencing indicated that the strain DI101 clearly belongs to the Serratia marcesc...

The neurotransmitter serotonin (5-HT) is involved in mood disorder aetiology and it has been reported that (organophosphate) OP exposure affects 5-HT turnover. The aim of this study was to elucidate the mechanism underlying OP effects on the adult 5-HT system. First, acute in vivo administration of the OP diazinon (0, 1.3, 13 or 39 mg/kg i.p.) to male Hooded Lister rats inhibited the activity o...

The biodisposition of cocaine and norcocaine in blood and tissues of immunological importance in B6C3F1 mice following exposure to cocaine or cocaine plus an organophosphate esterase inhibitor, diazinon, is presented. Analysis of specimens was by gas chromatography-mass spectrometry. Results from these studies indicate that pretreatment with diazinon significantly increases cocaine and norcocai...

There has been increasing interest in studying the various effects of organophosphate insecticides in humans and experimental animals. Only a few data are available on the effect of the organophosphate insecticide, diazinon, on lipid metabolism. The aim of this study was to evaluate the effect of diazinon on plasma lipid constituents in mammalian animals. The plasma levels of total cholesterol ...

The present study was aimed to evaluate the effects of tea and olive leaves extracts and their combination in male mice intoxicated with a sublethal concentration of diazinon. Exposure of mice to 6.5 mg/kg body weight of diazinon for seven weeks resulted in statistical increases of serum alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase, alkaline phosphatase, crea...

This paper describes the toxicity of organophosphorus pesticide diazinon in juvenile and adult terrestrial isopods Porcellio scaber (Isopoda, Crustacea). The woodlice were exposed to different concentrations of diazinon added to food (5, 10, 50, and 100 or 150 micrograms/g dry food). Weight change and food assimilation efficiency were determined two and four weeks after the exposure. The activi...