Of a series of ninety-six young male Syrian Golden hamsters, 13% developed lethargy, anorexia, diarrhoea and colocolic intussusception when their diet was changed from a basal laboratory-grade rodent chow to a nutritionally complete semi-purified diet. Histologically, the colon of the hamsters with intussusception had markedly reduced mucus production. Plasma levels of gastric inhibitory polype...

Fragments of 40 ovaries of various laboratory mammals, including mice, golden hamsters, rabbits and ferrets have been studied. The structures described in this paper were observed in some of the oocytes in the 14-day-old golden hamster ovary. The specimens in which they were present were obtained from 4 animals. After fixation for 60 min in chilled, buffered osmium tetroxide, the blocks were de...

The present paper records the availability of a new transplantable melanotic tumor in the Syrian golden hamster. A previous report (1) described the induction of multiple pigmented tumors in the Syrian golden hamster following the application to the skin of a single dose of the carcinogen 9,10dimethyl-l,2-benzanthracene. These tumors were sharply demarcated and located in the dermis and subcuta...

rugae), rat (8) and golden hamster (7). We showed that palatal growth rate, spacing and addition rate in mouse/rat were remarkably similar (with respect to the embryo size difference), and that increase to 9 rugae in mouse is achieved by postponing the end of the addition process (hypermorphosis). Such a heterochronic shift may be typical of 1 variations observed among muroid rodents. In contra...

The lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) isoenzyme distributions in tissues of the ICR mouse, Wistar rat, guinea pig and golden hamster were analyzed by histoelectrophoresis. Tissues obtained were as follows: liver, pancreas, stomach, small intestine, heart, femoral muscle, uterus, kidney, spleen, lymph node, cerebrum, spinal cord and erythrocyte. Histoelectrophoresis wa...

rugae), rat (8) and golden hamster (7). We showed that palatal growth rate, spacing and addition rate in mouse/rat were remarkably similar (with respect to the embryo size difference), and that increase to 9 rugae in mouse is achieved by postponing the end of the addition process (hypermorphosis). Such a heterochronic shift may be typical of 1 variations observed among muroid rodents. In contra...

rugae), rat (8) and golden hamster (7). We showed that palatal growth rate, spacing and addition rate in mouse/rat were remarkably similar (with respect to the embryo size difference), and that increase to 9 rugae in mouse is achieved by postponing the end of the addition process (hypermorphosis). Such a heterochronic shift may be typical of 1 variations observed among muroid rodents. In contra...

The present paper records the availability of a new transplantable melanotic tumor in the Syrian golden hamster. A previous report (1) described the induction of multiple pigmented tumors in the Syrian golden hamster following the application to the skin of a single dose of the carcinogen 9,10dimethyl-l,2-benzanthracene. These tumors were sharply demarcated and located in the dermis and subcuta...

This article describes a procedure which permits for the first time the isolation of the prion protein PrPc from the Syrian golden hamster in heterologous systems. Using a glutathione S-transferase (GST) fusion approach, milligram amounts of stable, soluble, and homogeneous GST::PrPc protein were obtained in Escherichia coli and with baculovirus-infected insect cells. Authentic PrPc was release...

Dyslipidemia has been widely proven to contribute to cardiovascular diseases and other metabolic disorders, especially in insulin resistance and type 2 diabetes. The overproduction of VLDL is a significant characteristic of dyslipidemia, indicating the dysfunction of hepatic lipid metabolism, from triglyceride synthesis to transport. The fructose-fed Syrian golden hamster is an established anim...